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非免疫功能低下宿主中由巨细胞病毒感染引起的病毒相关噬血细胞综合征和出血性空肠溃疡;罕见病例报告

Virus-associated hemophagocytic syndrome and hemorrhagic jejunal ulcer caused by cytomegalovirus infection in a non-compromised host; a case report of unusual entity.

作者信息

Ina Shinomi, Tani Masaji, Takifuji Katsunari, Yamazoe Shinji, Nakatani Yoshihiro, Yamaue Hiroki

机构信息

Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.

出版信息

Hepatogastroenterology. 2004 Mar-Apr;51(56):491-3.

PMID:15086189
Abstract

A 76-year-old man was admitted to our hospital with abdominal pain, nausea, and vomiting. The patient was diagnosed as ileus by abdominal radiography, which showed an enlarged bowel and an air-fluid level. Computed tomography of the abdomen showed a thickened intestinal wall. His general status suddenly worsened, and he was placed on a respirator and catecholamines to prevent acute respiratory distress syndrome, septic shock, and disseminated intravascular coagulation. He had continuous fresh anal bleeding. Total colonoscopy showed bloody stool originating from the ileum. Emergency operation was performed for hemorrhagic shock under general anesthesia. Intraoperative jejunal endoscopy revealed deep linear ulcers with bleeding in the jejunum, and 30 cm of the jejunum was resected. Histopathologic examination revealed cytomegalic cells with intranuclear inclusion bodies in the tissues surrounding the ulcers, and it was diagnosed as cytomegaloviral enterocolitis with hemophagocytic syndrome in a non-compromised adult.

摘要

一名76岁男性因腹痛、恶心和呕吐入院。腹部X线检查显示肠管扩张和气液平面,诊断为肠梗阻。腹部计算机断层扫描显示肠壁增厚。患者一般状况突然恶化,为预防急性呼吸窘迫综合征、感染性休克和弥散性血管内凝血,给予其呼吸机支持及使用儿茶酚胺类药物。患者持续出现新鲜肛门出血。全结肠镜检查显示便血源自回肠。在全身麻醉下因失血性休克行急诊手术。术中空肠内镜检查发现空肠有伴有出血的深部线性溃疡,切除了30厘米的空肠。组织病理学检查显示溃疡周围组织中有含核内包涵体的巨细胞,诊断为非免疫功能低下成人的巨细胞病毒性小肠结肠炎合并噬血细胞综合征。

相似文献

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Virus-associated hemophagocytic syndrome and hemorrhagic jejunal ulcer caused by cytomegalovirus infection in a non-compromised host; a case report of unusual entity.非免疫功能低下宿主中由巨细胞病毒感染引起的病毒相关噬血细胞综合征和出血性空肠溃疡;罕见病例报告
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Cytomegalovirus-induced massive small intestinal bleed. Case report and review of the literature.巨细胞病毒引起的大量小肠出血。病例报告及文献综述。
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Refractory ulcerative colitis complicated by a cytomegaloviral infection requiring surgery: report of a case.难治性溃疡性结肠炎合并巨细胞病毒感染需手术治疗:病例报告
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Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know.噬血细胞性淋巴组织细胞增生症与胃肠道出血:外科医生应了解的知识。
Case Rep Surg. 2015;2015:745848. doi: 10.1155/2015/745848. Epub 2015 Jun 25.
2
Reactivation versus primary CMV infection after splenectomy in immunocompetent patients.免疫功能正常患者脾切除术后巨细胞病毒再激活与原发性感染
Dig Dis Sci. 2007 Dec;52(12):3477-9. doi: 10.1007/s10620-006-9712-1. Epub 2007 Apr 12.