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儿童急性呼吸窘迫综合征的病因、临床及病理形态学方面

Etiological, clinical and pathomorphological aspects of acute respiratory distress syndrome in children.

作者信息

Nistor N, Dimitriu A G, Russu G, Cristogel F, Varlam L, Jităreanu C, Mihăilă D, Vlad A

机构信息

1st Pediatric Clinic, Faculty of Medicine, University of Medicine and Pharmacy Gr. T. Popa, Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 1998 Jul-Dec;102(3-4):96-9.

PMID:10756853
Abstract

Acute respiratory distress syndrome (ARDS) is the result of severe injuries of different etiologies of the capillary system in patients with previously healthy lungs, resulting in noncardiogenic pulmonary edema. The authors studied 42 infants in whom the histopathologic aspects were suggestive for ARDS. The etiologic factors of this syndrome were: severe gastroenteritis with hypovolemic or endotoxic shock (13 cases), sepsis (9 cases), fulminans purpura (2 cases), severe neurological disorders (13 cases), pulmonary infections (5 cases). In such conditions, if the infant presents hyperpnea followed by generalised cyanosis, refractory to oxygen therapy, and if there are clinical and radiologic signs of acute pulmonary edema, the diagnosis of ARDS must be considered and a complete intensive care therapy is compulsory in order to alleviate the severe prognosis of this syndrome.

摘要

急性呼吸窘迫综合征(ARDS)是既往肺部健康的患者因不同病因导致毛细血管系统严重损伤,进而引发非心源性肺水肿的结果。作者研究了42例组织病理学表现提示为ARDS的婴儿。该综合征的病因包括:伴有低血容量性或内毒素性休克的重症胃肠炎(13例)、败血症(9例)、暴发性紫癜(2例)、严重神经系统疾病(13例)、肺部感染(5例)。在这些情况下,如果婴儿出现呼吸急促,随后出现全身性发绀,对氧疗无效,并且存在急性肺水肿的临床和放射学征象,则必须考虑ARDS的诊断,为改善该综合征的严重预后,必须进行全面的重症监护治疗。

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