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干燥区深度与选定汽化切割电极的比较:动物基础研究

Comparison of the depth of the desiccated zone with selected vaporizing-cutting electrodes: a basic study in animals.

作者信息

Ishikawa N, Goya N, Iguchi Y, Toda F, Nishino S, Ishijima M, Toma H

机构信息

Departments of Urology and Institute of Biomedical Engineering, Tokyo Women's Medical University, Tokyo, Japan.

出版信息

BJU Int. 2000 Apr;85(6):754-8. doi: 10.1046/j.1464-410x.2000.00512.x.

Abstract

OBJECTIVE

To evaluate in an animal model the haemostatic efficacy of vaporizing-cutting (VC) electrodes recently developed for use in high-energy transurethral resection of the prostate (TURP).

MATERIALS AND METHODS

Four VC electrodes were assessed for their haemostatic efficacy in the muscle and liver of pigs (in vitro) and dogs (in vivo). The devices tested were the roller-cutting and Vapor Cut (Karl Storz GmbH, Germany); the Wedge (Boston Scientific Corp., Boston, USA); and the Uroloop (Endocare Inc., Irvine, CA). In each the depth of the desiccated zone was compared with that produced by a standard cutting loop electrode. Each electrode was attached to a scanning system (developed previously) that allowed the electrode pressure on the tissue surface (in 3% sorbitol solution) and the running speed to be adjusted. The same generator was used with all devices. The tissue (muscle or liver) was cut by running the electrode over the surface at 200, 250 or 300 W, with the loop electrode used as the reference. After completing the procedure, the surgical wound and the surrounding tissue were dissected out and the depth of the heat-affected zone (HAZ, defined as the desiccated zone) measured.

RESULTS

In pig muscle (stroke speed 5 mm/s) there was no significant difference in the depth of the HAZ between the four VC electrodes and the loop, or among the VC electrodes at any of the power levels tested. In pig liver (stroke speed 5 mm/s), the roller cutting and Vapor Cut electrodes produced a thicker HAZ than the loop at all power levels tested (P < 0.01). The Wedge electrode produced a significantly thicker HAZ than the loop at 200 and 300 W (P < 0.01). There were no significant differences in HAZ among the VC electrodes at any power level. In dog muscle in vivo (stroke speed 10 mm/s), the roller cutting, Vapor Cut and Wedge electrodes produced a significantly thicker HAZ at 250 W than the loop at 150 W (the usual power for TURP) (P < 0.01). There was no significant difference among the VC electrodes. In dog liver in vivo (stroke speed 10 mm/s), the roller cutting electrode produced a significantly thicker HAZ at 250 W than the loop at 150 W (P < 0.01).

CONCLUSIONS

The present VC electrodes produced a thicker desiccation zone at higher powers (200-300 W) than the standard loop at the usual power (150 W). The four VC electrodes produced a similar desiccation zone. With pig muscle and liver in vitro, regular loops used at a higher power created a desiccation zone that was 70-80% of the depth created by the VC electrodes.

摘要

目的

在动物模型中评估最近开发的用于高能经尿道前列腺切除术(TURP)的汽化切割(VC)电极的止血效果。

材料与方法

评估了四种VC电极在猪肌肉和肝脏(体外)以及犬类(体内)中的止血效果。测试的设备有滚切和汽化切割电极(德国卡尔史托斯公司);楔形电极(美国波士顿科学公司,波士顿);以及Uroloop电极(美国加利福尼亚州欧文市Endocare公司)。将每个电极产生的干燥区深度与标准切割环电极产生的深度进行比较。每个电极都连接到一个先前开发的扫描系统,该系统可以调节电极在组织表面(在3%山梨醇溶液中)的压力和运行速度。所有设备都使用同一台发生器。通过在组织(肌肉或肝脏)表面以200、250或300W的功率运行电极来进行切割,以环形电极作为对照。手术完成后,取出手术伤口和周围组织,测量热影响区(HAZ,定义为干燥区)的深度。

结果

在猪肌肉中(行程速度5mm/s),四种VC电极与环形电极之间以及在任何测试功率水平下的VC电极之间,HAZ深度均无显著差异。在猪肝脏中(行程速度5mm/s),在所有测试功率水平下,滚切和汽化切割电极产生的HAZ比环形电极厚(P<0.01)。楔形电极在200和300W时产生的HAZ比环形电极显著更厚(P<0.01)。在任何功率水平下,VC电极之间的HAZ无显著差异。在犬类体内肌肉中(行程速度10mm/s),滚切、汽化切割和楔形电极在250W时产生的HAZ比环形电极在150W(TURP的常用功率)时显著更厚(P<0.01)。VC电极之间无显著差异。在犬类体内肝脏中(行程速度10mm/s),滚切电极在250W时产生的HAZ比环形电极在150W时显著更厚(P<0.01)。

结论

当前的VC电极在较高功率(200 - 300W)下产生的干燥区比标准环形电极在常用功率(150W)下更厚。四种VC电极产生的干燥区相似。在体外猪肌肉和肝脏中,以较高功率使用的常规环形电极产生的干燥区深度是VC电极产生深度的70 - 80%。

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