Connelly N R, Parker R K, Rahimi A, Gibson C S
Department of Anesthesiology, Baystate Medical Center, Springfield, MA 01199, USA.
Headache. 2000 Apr;40(4):316-9. doi: 10.1046/j.1526-4610.2000.00047.x.
To determine the efficacy of sumatriptan in the management of patients presenting for an epidural blood patch for the management of postdural puncture headache.
Postdural puncture headache can be quite severe, requiring invasive therapy (ie, epidural blood patch). Sumatriptan has been used successfully in patients with postdural puncture headache, however, its use has not been investigated in a controlled fashion.
Ten patients with postdural puncture headache presenting for an epidural blood patch were given either saline or sumatriptan subcutaneously. The severity of the headache was evaluated at baseline and 1 hour following injection. If the headache remained severe, an epidural blood patch was performed.
Only one patient in each group received relief from the injection.
We do not recommend sumatriptan in patients who have exhausted conservative management of postdural puncture headache.
确定舒马曲坦用于硬膜外血贴治疗硬膜穿刺后头痛患者的疗效。
硬膜穿刺后头痛可能相当严重，需要进行侵入性治疗（即硬膜外血贴）。舒马曲坦已成功用于硬膜穿刺后头痛患者，然而，其使用尚未以对照方式进行研究。
10例因硬膜外血贴前来治疗的硬膜穿刺后头痛患者，皮下注射生理盐水或舒马曲坦。在基线和注射后1小时评估头痛的严重程度。如果头痛仍然严重，则进行硬膜外血贴。
每组仅1例患者注射后疼痛缓解。
对于硬膜穿刺后头痛保守治疗无效的患者，我们不推荐使用舒马曲坦。
