Pawlotsky J M
Department of Bacteriology and Virology and INSERM U99, Hôpital Henri Mondor, Université Paris XII, Créteil, France.
J Viral Hepat. 1999 Jul;6 Suppl 1:47-8. doi: 10.1046/j.1365-2893.1999.00004.x.
The hepatitis C virus (HCV) non-structural (NS) 5A protein appears to play an important regulatory role on viral replication and could also be involved in viral pathogenesis. HCV resistance to interferon is a complex mechanism involving multiple causes, among which certain NS5A functions could play a role.
丙型肝炎病毒(HCV)非结构(NS)5A蛋白似乎在病毒复制中发挥重要调节作用,并且可能也参与病毒致病过程。HCV对干扰素的耐药性是一种涉及多种原因的复杂机制,其中某些NS5A功能可能起作用。