Malhotra A, Krilov L R
Division of Pediatric Infectious Disease, North Shore University Hospital-New York University School of Medicine, Manhasset, USA.
Pediatr Clin North Am. 2000 Apr;47(2):353-72, vi-vii. doi: 10.1016/s0031-3955(05)70211-x.
This article is an overview of the epidemiology and spectrum of clinical disease attributed to influenza and respiratory syncytial virus in children. It separately discusses the pathogenesis of the two diseases and the host responses to the viruses to emphasize each infection's significance and need for a vaccine. Updates on current preventive measures and a preview of potential future vaccine developments are presented.
本文概述了儿童流感和呼吸道合胞病毒所致临床疾病的流行病学及疾病谱。分别讨论了这两种疾病的发病机制以及宿主对病毒的反应,以强调每种感染的重要性及疫苗需求。还介绍了当前预防措施的最新情况以及对未来潜在疫苗研发的展望。