Walch C, Stammberger H, Anderhuber W, Unger F, Köle W, Feichtinger K
Department of ENT, University of Graz, Austria.
Laryngoscope. 2000 Apr;110(4):635-40. doi: 10.1097/00005537-200004000-00018.
To describe a new treatment modality of olfactory neuroblastoma consisting of endoscopic nasal and paranasal sinus surgery and stereotactic radiosurgery.
Retrospective review of three patients suffering from olfactory neuroblastoma.
Review of the charts, the computed tomography, and magnetic resonance imaging scans, the operation reports, radiosurgical data, and follow-up.
All three patients remained free of disease with excellent quality of life in respective follow-up periods of 71, 50, and 39 months.
The combination of two minimally invasive therapies, endoscopic sinus surgery and stereotactic radiosurgery, provide a reliable new approach to the treatment of a series of olfactory neuroblastomas that offers excellent quality of life, less injury to the patient, fewer side-effects, and fewer long-term effects than other treatment strategies.
描述一种由鼻内镜鼻窦手术和立体定向放射外科组成的嗅神经母细胞瘤新治疗方式。
对3例嗅神经母细胞瘤患者进行回顾性研究。
查阅病历、计算机断层扫描和磁共振成像扫描、手术报告、放射外科数据及随访资料。
在分别为71、50和39个月的随访期内，所有3例患者均无疾病复发，生活质量良好。
内镜鼻窦手术和立体定向放射外科这两种微创治疗方法相结合，为一系列嗅神经母细胞瘤的治疗提供了一种可靠的新方法，与其他治疗策略相比，该方法能提供良好的生活质量，对患者损伤小，副作用少，长期影响也少。
