Ishii K, Amagai M, Ohata Y, Shimizu H, Hashimoto T, Ohya K, Nishikawa T
Department of Dermatology, Keio University School of Medicine, Saiseikai Central Hospital, Tokyo, Japan.
J Am Acad Dermatol. 2000 May;42(5 Pt 2):859-61. doi: 10.1016/s0190-9622(00)90253-6.
We describe a patient with pemphigus foliaceus (PF) in whom pemphigus vulgaris (PV) subsequently developed. The clinical change was accompanied by a shift of autoantibody profile confirmed by enzyme-linked immunosorbent assay. Antidesmoglein (Dsg) 1 antibodies alone were detected in the PF stage, whereas both anti-Dsg3 and anti-Dsg1 antibodies were detected in the PV stage.