Fein A M, Calalang-Colucci M G
Department of Medicine, State University of New York, Stony Brook School of Medicine, USA.
Crit Care Clin. 2000 Apr;16(2):289-317. doi: 10.1016/s0749-0704(05)70111-1.
Sepsis remains the leading cause of ARDS, and ARDS is still an often fatal condition. With our expanding knowledge of the pathobiologic mechanisms and the relationship between these two entities, early recognition, treatment, and prevention of sepsis may prevent or hasten recovery from ARDS. Understanding the biologic markers involved in the complex inflammatory response of sepsis and acute lung injury offers the possibility of future investigations to target treatment based on these mediators.
脓毒症仍然是急性呼吸窘迫综合征（ARDS）的主要病因，而ARDS仍然是一种往往致命的病症。随着我们对这两种疾病的病理生物学机制及其相互关系的认识不断扩展，早期识别、治疗和预防脓毒症可能会预防ARDS或加速其康复。了解脓毒症和急性肺损伤复杂炎症反应中涉及的生物标志物，为未来基于这些介质进行靶向治疗的研究提供了可能性。
