Palomeras E, Sanz P, Cano A, Fossas P
Unit of Neurology, Hospital de Mataró, Spain.
Arch Neurol. 2000 Apr;57(4):570-1. doi: 10.1001/archneur.57.4.570.
We present a 68-year-old patient with essential tremor who was treated with propranolol hydrochloride (80 mg daily) and gabapentin (900 mg daily) after a history of mild success of gabapentin alone in relieving his symptoms. The patient had several daily episodes of paroxysmal dystonic movements in both hands. After reducing the propranolol dose to 40 mg daily, the dystonic movements resolved. This case suggests a synergistic effect between propranolol and gabapentin.
我们报告一名68岁的特发性震颤患者，该患者在单独使用加巴喷丁缓解症状仅取得轻度成功后，接受了盐酸普萘洛尔（每日80毫克）和加巴喷丁（每日900毫克）治疗。该患者双手每天有几次阵发性肌张力障碍运动发作。将普萘洛尔剂量减至每日40毫克后，肌张力障碍运动消失。该病例提示普萘洛尔和加巴喷丁之间存在协同作用。
