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[再狭窄的治疗]

[Treatment of restenosis].

作者信息

Raithel D, Schunn C, Hetzel G, Ritter W

机构信息

Klinik für Gefässchirurgie, Klinikum Nürnberg-Süd.

出版信息

Zentralbl Chir. 2000;125(3):270-4.

Abstract

Carotid restenosis after endarterectomy is observed in up to 24.1% of patients with long-term follow up. Indication for reintervention in asymptomatic patients however should be reserved for greater than 80% stenosis. Treatment options include repeat surgical reconstruction as well as intraoperative or percutaneous balloon angioplasty +/- stenting. We compared our past experience with 66 operative reconstructions in 64 patients with a recent series of 60 patients who underwent intraoperative balloon-dilatation and stenting. After conventional surgery 2 patients (3.1%) suffered a permanent neurological deficit, one patient developed a TIA (1.5%). After intraoperative dilation and stenting 8 patients (13.3%) suffered a stroke; 2 patients died after surgery (one stroke, one myocardial infarction) (mortality 3.3%). When compared to conventional operative repair intraoperative carotid balloon angioplasty and stenting of restenosis is complicated by a substantial increase in morbidity and mortality and cannot be recommended as routine therapy.

摘要

在长期随访中,高达24.1%的动脉内膜切除术后患者会出现颈动脉再狭窄。然而,无症状患者再次干预的指征应为狭窄程度大于80%。治疗选择包括重复手术重建以及术中或经皮球囊血管成形术+/-支架置入术。我们将过去64例患者行66次手术重建的经验与最近一组60例行术中球囊扩张和支架置入术的患者进行了比较。传统手术后,2例患者(3.1%)出现永久性神经功能缺损,1例患者发生短暂性脑缺血发作(1.5%)。术中扩张和支架置入术后,8例患者(13.3%)发生中风;2例患者术后死亡(1例中风,1例心肌梗死)(死亡率3.3%)。与传统手术修复相比,术中颈动脉球囊血管成形术和再狭窄支架置入术的并发症显著增加,发病率和死亡率显著升高,因此不建议作为常规治疗方法。

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