Kitamura S, Yagihara T, Niwaya K, Uemura H, Bando K, Kobayashi J, Sasako Y, Minatoya K, Kawahira Y, Yoshikawa Y, Koizumi N, Nakatani T
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Japan.
Kyobu Geka. 2000 Apr;53(4):275-80.
Eight patients, 4 males and 4 females ranging in age from 10 to 54 years (mean 27 +/- 13 years) underwent the Ross operation using a cryopreserved pulmonary homograft harvested by and cryopreserved in our institutional "Tissue Bank". Seven patients had a congenital bicuspid aortic valve and 3 patients had had healed infective endocarditis of the aortic valve. Four young female patients wanted to have a baby after operation. The Ross procedure was carried out utilizing aortic root replacement techniques in all patients. All patients survived and are currently in NYHA class 1, but 2 cardiac events occurred in 2 patients during the mean follow-up term of 29 +/- 19 months. The one was the anastomic stenosis between the homograft and distal pulmonary artery treated by balloon dilatation and the other was ventricular tachycardia eventually managed by the insertion of an ICD. Pulmonary autograft valve regurgitation is present in 3 patients, but it is not progressive up to the present time. Pulmonary homograft valves function well in all patients. The Ross operation for adolescents and young adults should become more popular along with more easy availability of homograft valves based upon the establishment of the "Homograft Valve Bank" system in Japan.
8例患者（4例男性，4例女性，年龄10至54岁，平均27±13岁）接受了Ross手术，使用的是由我院“组织库”采集并冷冻保存的同种异体肺动脉移植物。7例患者患有先天性二叶主动脉瓣，3例患者曾有过主动脉瓣感染性心内膜炎且已治愈。4例年轻女性患者术后希望生育。所有患者均采用主动脉根部置换技术进行Ross手术。所有患者均存活，目前纽约心脏协会（NYHA）心功能分级为1级，但在平均29±19个月的随访期内，2例患者发生了2次心脏事件。1例是同种异体移植物与远端肺动脉之间的吻合口狭窄，通过球囊扩张治疗；另1例是室性心动过速，最终通过植入植入式心脏复律除颤器（ICD）进行处理。3例患者存在自体肺动脉瓣反流，但目前尚未进展。所有患者的同种异体肺动脉瓣功能良好。随着日本“同种异体瓣膜库”系统的建立，同种异体瓣膜更容易获得，Ross手术在青少年和年轻成人中应该会更受欢迎。
