Hernández Valencia M, Becerril Flores L C
Unidad de Investigación en Enfermedades Endocrinas, IMSS, México.
Ginecol Obstet Mex. 2000 Feb;68:70-6.
Postpartum insertion of the intrauterine device (IUD) can provide an effective and convenient means of contraception. As a result, the use of IUD's has steadily increased, and the Family Planning Program recommends it because it offers many advantages. However, a major risk associated with the use of IUD's is the possibility of its expulsion, which ranges from 4 to 60%. Furthermore, 20% of women who expelled IUD's were unaware that it occurred, thus increasing their susceptibility to unwanted pregnancies. IUD's modified by the addition of biodegradable strands of chromic suture at time of implantation are thought to be less likely to be expelled, as the sutures anchor the IUD more firmly to the endometrium, and it is possible that the use of these sutures may decrease the risk of expulsion. Therefore we determined if the chromic extension to IUD enhance retention and decreased the rate of expulsion. In one year of study, 150 women received a modified IUD (TCu 380) with chromic catgut number 0 (ccO) in the transversal arm within 10 minutes of delivery of the placenta. However, only 84 women completed the follow-up study. To evaluate IUD expulsion, exploratory examinations were conducted during the immediate postpartum, at 7 days postpartum and at 6 weeks after delivery. We determined the presence or expulsion of the IUD in these three periods postpartum. Other parameters such as parity, age and marital status were also considered. A total of 14 modified IUD's (16.6%) were expelled. This represents a similar frequency of expulsion both during the immediate postpartum and the 7 days postpartum period. There was no significant difference in the rate of expulsion between the two periods. Moreover, there was no expulsion at 6 weeks postpartum. The primiparity women had the highest percentage of expulsion (22.8%). Single mothers either living with or without their sexual partner had expulsion rates of 20.6 and 20.5%, respectively. The highest rate of expulsion when we considered age was in women younger than 30 years of age. There was only one case of expulsion where the mother was unaware of its occurrence. The results described here indicate that age, parity and civil status have no direct influence on expulsion of modified IUD's with chrome extensions. In all postpartum periods studied the p-value was greater than 0.05. Six weeks postpartum was the only time at which there was no IUD expulsion. This is most likely a consequence of decreased uterine cavity size and closure cervix. The modified IUD TCu 380 with chrome strands shows a rate of expulsion similar to other modified IUD's as evidenced in the literature. However, there is a lower rate of expulsion than in unmodified IUD's. It is an important to rote that incomplete expulsion of modified IUD's in this study was considered a total expulsion which represent loss of contraceptive effectiveness. On the contrary, if we had considered only completely expelled IUD's in this study, the percentage would have been significantly lower, as only one total expulsion was found. Further studies are necessary to investigate consecutive expulsions of the TCu 380 modified IUD.
产后放置宫内节育器(IUD)可提供一种有效且便捷的避孕方式。因此,IUD的使用稳步增加,计划生育项目推荐使用它是因为它有诸多优点。然而,使用IUD的一个主要风险是其可能被排出,排出率在4%至60%之间。此外,20%排出IUD的女性并未意识到IUD已排出,从而增加了她们意外怀孕的易感性。植入时添加可生物降解的铬制缝线的改良IUD被认为排出可能性较小,因为这些缝线能将IUD更牢固地固定在子宫内膜上,且使用这些缝线可能会降低排出风险。因此,我们确定铬制延长部分是否能增强IUD的留存并降低排出率。在为期一年的研究中,150名女性在胎盘娩出后10分钟内接受了在横臂带有0号铬制肠线(cc0)的改良IUD(TCu 380)。然而,只有84名女性完成了随访研究。为评估IUD排出情况,在产后即刻、产后7天及产后6周进行了探查性检查。我们确定了这三个产后时期IUD是否存在或已排出。还考虑了其他参数,如产次、年龄和婚姻状况。共有14个改良IUD(16.6%)被排出。这表明产后即刻和产后7天期间的排出频率相似。这两个时期的排出率没有显著差异。此外,产后6周没有IUD排出。初产妇的排出百分比最高(22.8%)。与性伴侣同住或不同住的单身母亲的排出率分别为20.6%和20.5%。考虑年龄因素时,排出率最高的是年龄小于30岁的女性。只有一例排出情况母亲未意识到。此处描述的结果表明,年龄、产次和婚姻状况对带有铬制延长部分的改良IUD的排出没有直接影响。在所有研究的产后时期,p值均大于0.05。产后6周是唯一没有IUD排出的时间。这很可能是子宫腔大小减小和宫颈闭合的结果。带有铬制缝线的改良IUD TCu 380的排出率与文献中其他改良IUD相似。然而,其排出率低于未改良的IUD。重要的是要指出,本研究中改良IUD的不完全排出被视为完全排出,这意味着避孕效果丧失。相反,如果本研究中只考虑完全排出的IUD,百分比会显著更低,因为只发现了一例完全排出。有必要进一步研究TCu 380改良IUD的连续排出情况。