Arowojolu A O, Otolorin E O, Ladipo O A
Department of Obstetrics & Gynaecology, University College Hospital, Ibadan, Nigeria.
Afr J Med Med Sci. 1995 Mar;24(1):59-65.
An evaluation of the performances of copper T 380A (TCU 380A) and multiload copper 375/250 (MLCU 375/250) intrauterine contraceptive devices (IUCDS) was carried out at University College Hospital, Ibadan, Nigeria (UCH) in a clinical comparative trial. The IUCDS showed similar low vent rates at one year of continuous use. The difference in cumulative net probabilities for termination due to pelvic inflammatory disease was weakly significant at the sixth month of follow up with MLCU 250 having the highest rate. (TCU 380A-0%; MLCU 375-0%; MLCU 250-3.1%; X2 = 6.0; P < 0.05). This significant difference disappeared by the twelfth month of continuous use. Likewise, the difference in cumulative net probabilities for overall termination was significant at six months and insignificant at twelve months of follow up. The continuation rate after one year were 86%, 92% and 87% respectively for TCU 380A, MLCU 375 and MLCU 250. These rates were higher than 80% and 51% quoted for the previously available Lippes loop in the same environment [1,2]. It was therefore concluded that the three IUCDS are comparable in performances in the first year of use and could be used at our family planning clinic or any other clinic in a similar setting.
在尼日利亚伊巴丹大学学院医院（UCH）进行了一项临床对比试验，对铜T 380A（TCU 380A）和多负载铜375/250（MLCU 375/250）宫内节育器（IUCD）的性能进行了评估。这些宫内节育器在连续使用一年时显示出相似的低停用率。在随访的第六个月，因盆腔炎导致终止使用的累积净概率差异微弱显著，其中MLCU 250的发生率最高。（TCU 380A为0%；MLCU 375为0%；MLCU 250为3.1%；X2 = 6.0；P < 0.05）。到连续使用的第十二个月时，这一显著差异消失。同样，总体终止使用的累积净概率差异在随访六个月时显著，在十二个月时不显著。TCU 380A、MLCU 375和MLCU 250一年后的续用率分别为86%、92%和87%。这些续用率高于在相同环境中之前使用的Lippes环所引用的80%和51%[1,2]。因此得出结论，这三种宫内节育器在使用的第一年性能相当，可在我们的计划生育诊所或类似环境中的任何其他诊所使用。
