Kinjo T, Iwamasa T
Department of Pathology, Ryukyu University School of Medicine.
Nihon Rinsho. 2000 Apr;58(4):864-70.
Herpes simplex virus type 1 (HSV1) encephalitis is commonly observed, but HSV1 myelitis is rare. On the other hand, HSV2 is common etiologic agent for ascending necrotizing myelitis associated with diabetes mellitus, malignant tumors, AIDS and immunocompromised hosts. It is suggested that latent infection of the virus of root ganglia or primary infected virus is possibly followed by spread of infection to the central nervous system, particularly in immunocompromised patients. In this report, pathological findings and clinical symptoms of our recent encephalitis and myelitis cases infected with HSV2 and HSV1 are described.
单纯疱疹病毒1型（HSV1）脑炎较为常见，但HSV1脊髓炎罕见。另一方面，HSV2是与糖尿病、恶性肿瘤、艾滋病及免疫功能低下宿主相关的上行性坏死性脊髓炎的常见病原体。提示病毒在脊神经节的潜伏感染或原发性感染病毒可能继而扩散至中枢神经系统，尤其是在免疫功能低下的患者中。本报告描述了我们近期诊治的HSV2和HSV1感染的脑炎及脊髓炎病例的病理表现和临床症状。
