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猫的脊髓交感反射与动脉高血压的发病机制

Spinal sympathetic reflexes in the cat and the pathogenesis of arterial hypertension.

作者信息

Malliani A, Lombardi F, Pagani M, Recordati G, Schwartz P J

出版信息

Clin Sci Mol Med Suppl. 1975 Jun;2:259s-260s. doi: 10.1042/cs048259s.

Abstract
  1. In vagotomized anaesthetized cats with both common carotid arteries occluded, stretch of the thoracic aorta induced reflex increases in arterial blood pressure, heart rate and left ventricular dP/dtmax. Similar responses were obtained in cats with spinal transection at the level of the first cervical nerve roots. 2. The hypothesis is advanced that sympathetic excitatory reflexes may contribute to the maintenance of hypertension through positive feedback.
摘要
  1. 在双侧颈总动脉结扎的迷走神经切断麻醉猫中,牵拉胸主动脉可引起动脉血压、心率和左心室dp/dtmax反射性升高。在第一颈神经根水平进行脊髓横断的猫中也获得了类似的反应。2. 有人提出假说,交感神经兴奋性反射可能通过正反馈有助于维持高血压。

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