Heegaard E D, Kerndrup G B, Carlsen N T, Schmiegelow K, Hornsleth A K
Klinisk mikrobiologisk afdeling, H:S Rigshospitalet, København.
Ugeskr Laeger. 1999 Nov 22;161(47):6501-2.
A three-year-old boy was diagnosed with acute lymphoblastic leukemia. Two years later, while on maintenance chemotherapy, the patient was readmitted due to thrombocytopenia. The thrombocytopenia was caused by parvovirus B19 infection as evidenced by the finding of specific DNA in serum and bone marrow samples. Previous reports have highlighted the role of parvovirus B19 as a haematological pitfall and the present case shows that this virus has the potential to mimic a leukemic relapse.
一名三岁男孩被诊断出患有急性淋巴细胞白血病。两年后,在维持化疗期间,该患者因血小板减少症再次入院。血清和骨髓样本中发现特定DNA,证明血小板减少症是由B19细小病毒感染引起的。先前的报告强调了B19细小病毒作为血液学陷阱的作用,本病例表明该病毒有可能模仿白血病复发。