MMWR Morb Mortal Wkly Rep. 2000 Apr 7;49(13):278-81.
Infections with the soil-transmitted intestinal helminths (i.e., Ascaris lumbricoides, Trichuris trichiura, and hookworm), estimated to affect approximately 1 billion persons, are among the most common and widespread human infections. Among children aged <5 years, intestinal helminth infections cause malnutrition and anemia, two important causes of mortality. Anthelminthic treatment (deworming) improves nutritional status of school-aged children. The World Health Organization and the United Nations Children's Fund (UNICEF) have developed guidelines that include interventions for anemia and malnutrition in the integrated management of childhood illness (IMCI) for children aged <5 years seen at first-level health-care facilities in developing countries. Under the IMCI guidelines, in geographic areas where hookworm or Trichuris infections are endemic, children aged 2-4 years with palmar pallor are treated with an anthelminthic drug. This report summarizes an investigation of the use of palmar pallor as an indication for anthelminthic treatment among ill children aged 2-4 years seen at first-level health-care facilities in rural western Kenya; the investigation found that palmar pallor was associated with anemia but not with intestinal helminth infection.
土壤传播的肠道蠕虫(即蛔虫、鞭虫和钩虫)感染估计影响约10亿人,是最常见和广泛传播的人类感染之一。在5岁以下儿童中,肠道蠕虫感染会导致营养不良和贫血,这是两个重要的死亡原因。驱虫治疗可改善学龄儿童的营养状况。世界卫生组织和联合国儿童基金会(UNICEF)制定了相关指南,其中包括在发展中国家一级保健机构对5岁以下儿童进行儿童疾病综合管理(IMCI)时针对贫血和营养不良的干预措施。根据IMCI指南,在钩虫或鞭虫感染流行的地理区域,2至4岁手掌苍白的儿童用驱虫药治疗。本报告总结了对肯尼亚西部农村一级保健机构中2至4岁患病儿童使用手掌苍白作为驱虫治疗指征的调查;调查发现手掌苍白与贫血有关,但与肠道蠕虫感染无关。