Dickerson L M, Carek P J
Department of Family Medicine, Medical University of South Carolina, Charleston 29406, USA.
Am Fam Physician. 2000 Apr 1;61(7):2131-8, 2143.
Obesity is a common health problem in the United States, and effective treatment is challenging. Obesity is associated with an increased mortality rate and risk factors such as hypertension, hyperlipidemia and diabetes mellitus. Numerous treatments are available for obesity. Behavioral therapy, surgery and pharmacologic treatment have been used with varying degrees of success. Older anorectic agents have significant side effects and limited benefit, and some have even been withdrawn from the U.S. market because of a possible association with cardiovascular complications. The safety of newer agents must be extensively evaluated before widespread use is recommended. Therefore, behavioral therapy, including regular exercise and the development of healthy eating habits, continues to be the best treatment for long-term weight loss.
肥胖是美国常见的健康问题，有效治疗颇具挑战。肥胖与死亡率上升以及高血压、高脂血症和糖尿病等风险因素相关。肥胖有多种治疗方法。行为疗法、手术和药物治疗都已应用，且取得了不同程度的成功。较老的食欲抑制剂有显著副作用且益处有限，有些甚至因可能与心血管并发症有关而被撤出美国市场。在建议广泛使用之前，必须对新型药物的安全性进行广泛评估。因此，行为疗法，包括定期锻炼和养成健康饮食习惯，仍然是长期减肥的最佳治疗方法。
