赋予肿瘤抑制因子新功能

Teaching tumour suppressors new tricks.

作者信息

McCartney B M, Peifer M

出版信息

Nat Cell Biol. 2000 Apr;2(4):E58-60. doi: 10.1038/35008685.

Abstract

Examination of the tumour suppressor adenomatous polyposis coli (APC) has shown that it may be multifunctional. Recent work has demonstrated dynamic interactions of APC with the microtubule cytoskeleton, supporting the idea that APC has an important function in cell migration.

摘要

对肿瘤抑制基因腺瘤性息肉病大肠杆菌（APC）的研究表明，它可能具有多种功能。最近的研究工作已证实APC与微管细胞骨架之间存在动态相互作用，这支持了APC在细胞迁移中具有重要功能的观点。