Kitsanou M, Andreopoulou E, Bai M K, Elisaf M, Drosos A A
Department of Internal Medicine, Medical School, University of Ioannina, Greece.
Lupus. 2000;9(2):140-3. doi: 10.1191/096120300678828037.
Lymphadenopathy (LAP) is a frequent sign of systemic lupus erythematosus (SLE). The lymph nodes are usually soft, nontender, varying in size from 0.5 cm to several centimeters. However, generalized LAP in SLE is extremely rare, while to our knowledge, the presentation of extensive LAP with blocks of retrosternal, mesenteric, and retroperitoneal nodes has not been previously reported as the first clinical manifestation of the disease. In this report we describe a patient with extensive LAP and active SLE and we point out that generalized LAP should be included among the clinical findings indicating disease activity in SLE patients.
淋巴结病（LAP）是系统性红斑狼疮（SLE）的常见体征。淋巴结通常质地柔软，无压痛，大小从0.5厘米到几厘米不等。然而，SLE患者出现全身性LAP极为罕见，而就我们所知，以前尚未有胸骨后、肠系膜和腹膜后淋巴结肿大的广泛性LAP作为该疾病首发临床表现的报道。在本报告中，我们描述了一名患有广泛性LAP和活动性SLE的患者，并指出全身性LAP应纳入提示SLE患者疾病活动的临床发现之中。
