产β-内酰胺酶的人心杆菌所致感染性心内膜炎并发进行性心力衰竭
Infective endocarditis complicated with progressive heart failure due to beta-lactamase-producing Cardiobacterium hominis.
作者信息
Lu P L, Hsueh P R, Hung C C, Teng L J, Jang T N, Luh K T
机构信息
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
出版信息
J Clin Microbiol. 2000 May;38(5):2015-7. doi: 10.1128/JCM.38.5.2015-2017.2000.
Abstract
We describe a 66-year-old woman with infective endocarditis due to Cardiobacterium hominis whose condition, complicated by severe aortic regurgitation and congestive heart failure, necessitated aortic valve replacement despite treatment with ceftriaxone followed by ciprofloxacin. The blood isolate of C. hominis produced beta-lactamase and exhibited high-level resistance to penicillin (MIC, >==256 microgram/ml) and reduced susceptibility to vancomycin (MIC, 8 microgram/ml).
摘要
我们描述了一名66岁因人心杆菌感染性心内膜炎的女性患者，其病情因严重主动脉瓣反流和充血性心力衰竭而复杂化，尽管接受了头孢曲松随后环丙沙星的治疗，但仍需要进行主动脉瓣置换。人心杆菌的血液分离株产生β-内酰胺酶，对青霉素表现出高水平耐药（MIC，≥256微克/毫升），对万古霉素敏感性降低（MIC，8微克/毫升）。
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