Diallo D, Aubard Y, Piver P, Baudet J H
Service de Gynécologie-Obstétrique, CHU Limoges, 2, avenue Martin Luther King, 87042 Limoges cedex.
J Gynecol Obstet Biol Reprod (Paris). 2000 Apr;29(2):131-41.
Heterotopic pregnancy, also called combined pregnancy, associates extra-uterine pregnancy and intra-uterine pregnancy. We report five cases of heterotopic pregnancy illustrating this condition and reviewed the recent literature from 1994 to 1999. We compared the results of this review with earlier data in the literature from 1971 to 1993. We observed that therapeutic management of the extra-uterine pregnancy and course of the intra-uterine pregnancy have changed little over this period. Conversely, the frequency of heterotopic pregnancy has steadily increased since the development of medically assisted reproduction, although spontaneous cases continue to occur. The diagnosis of heterotopic pregnancy is often difficult as the symptomatology is often misleading. Transvaginal ultrasound generally gives the diagnosis which may be confirmed by laparoscopy, allowing treatment of the extra-uterine pregnancy. Maternal and intra-uterine fetal prognosis depends on early diagnosis which should be made, if possible, prior to termination of the extra-uterine pregnancy.
异位妊娠，也称为复合妊娠，是指宫外妊娠与宫内妊娠同时存在。我们报告了5例异位妊娠病例以说明这种情况，并回顾了1994年至1999年的近期文献。我们将此次回顾的结果与1971年至1993年文献中的早期数据进行了比较。我们观察到，在此期间，宫外妊娠的治疗处理及宫内妊娠的病程变化不大。相反，自医学辅助生殖技术发展以来，异位妊娠的发生率稳步上升，尽管仍有自然发生的病例。异位妊娠的诊断往往困难，因为其症状常常具有误导性。经阴道超声检查通常可作出诊断，腹腔镜检查可予以证实，从而得以治疗宫外妊娠。母婴及宫内胎儿的预后取决于早期诊断，若有可能，应在终止宫外妊娠之前作出诊断。
