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皮肤非结核分枝杆菌感染

Nontuberculous mycobacterial infections of the skin.

作者信息

Weitzul S, Eichhorn P J, Pandya A G

机构信息

Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, USA.

出版信息

Dermatol Clin. 2000 Apr;18(2):359-77, xi-xii. doi: 10.1016/s0733-8635(05)70182-0.

Abstract

Nontuberculous mycobacteria are playing an increasingly important role in human disease owing to higher prevalence of antibiotic resistance and immunodeficiency. These organisms cause a variety of cutaneous findings which are often misdiagnosed by the clinician. Compounding this problem is the fact that most mycobacteria require special culture conditions, which if not specifically requested, are frequently not used. Recognition of susceptible patients is imperative and is not limited to the immunocompromised. Successful treatment of mycobacterial infections requires knowledge of currently available and recommended antibiotics followed by tailoring of the antimicrobial regimen after sensitivity testing is performed.

摘要

由于抗生素耐药性和免疫缺陷的患病率较高,非结核分枝杆菌在人类疾病中发挥着越来越重要的作用。这些微生物会导致多种皮肤表现,临床医生常常会误诊。使这个问题更加复杂的是,大多数分枝杆菌需要特殊的培养条件,如果没有特别要求,这些条件常常不会被采用。识别易感患者至关重要,且不限于免疫功能低下者。成功治疗分枝杆菌感染需要了解目前可用的和推荐的抗生素,然后在进行药敏试验后调整抗菌方案。

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