烧伤毒素的分离及其免疫化学特性
Isolation and immunochemical properties of burn toxin.
作者信息
Kubica J, Grzybowski J, Kwiek S, Rysińska A, Bogusławska-Kubin J, Witecki J, Przystupa J, Bukowska B
出版信息
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):223-5.
PMID:107918
Abstract
Human skin and the skin of some laboratory animals was minced, scalded and homogenized. The preparation from scalded human skin (the "crude burn toxin") revealed to be highly toxic to mice after i.v. administration. It was found by immunodiffusion and immunoelectrophoresis, that the urea and buthanol extracts of the crude "toxin" contain tissue antigens which were absent in a control preparation from a native (non scalded) skin.
摘要
将人类皮肤和一些实验动物的皮肤切碎、烫煮并匀浆。烫伤的人类皮肤制备物（“粗制烧伤毒素”）经静脉注射后对小鼠显示出高毒性。通过免疫扩散和免疫电泳发现，粗制“毒素”的尿素和丁醇提取物含有组织抗原，而来自天然（未烫伤）皮肤的对照制备物中不存在这些抗原。
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