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儿童晚期的耳颞(弗雷)综合征:一种表现为味觉性潮红、类似食物过敏的不寻常变异型。

Auriculotemporal (Frey) syndrome in late childhood: an unusual variant presenting as gustatory flushing mimicking food allergy.

作者信息

Kaddu S, Smolle J, Komericki P, Kerl H

机构信息

Department of Dermatology, University of Graz, Graz, Austria.

出版信息

Pediatr Dermatol. 2000 Mar-Apr;17(2):126-8. doi: 10.1046/j.1525-1470.2000.01729.x.

DOI:10.1046/j.1525-1470.2000.01729.x
PMID:10792802
Abstract

Auriculotemporal or Frey syndrome is characterized mainly by recurrent episodes of facial gustatory flushing and/or sweating, limited to the cutaneous distribution of the auriculotemporal nerve. Although relatively common in adults following injury to the auriculotemporal nerve or parotid disease, the condition has rarely been reported in children. Moreover, in childhood, auriculotemporal syndrome has been described mainly in infancy and early childhood as a sequel of perinatal birth trauma resulting from assisted forceps delivery. We report a 13-year-old girl with a 2-month history of recurrent, painless, preauricular gustatory flushing without sweating, initially suspected to be a food allergy. Detailed inquiry revealed a history of a bicycle accident with mandibular condyle fracture 7 years prior to the onset of symptoms. Our patient demonstrates an unusual presentation of auriculotemporal syndrome in late childhood as gustatory flushing mimicking food allergy. Awareness of this variant is essential for prompt recognition, thus avoiding unnecessary laboratory tests, especially as this condition usually resolves spontaneously.

摘要

耳颞部或弗雷综合征主要表现为面部味觉性潮红和/或出汗反复发作,局限于耳颞神经的皮肤分布区域。虽然在成人中,耳颞神经损伤或腮腺疾病后较为常见,但儿童病例鲜有报道。此外,在儿童期,耳颞部综合征主要被描述为婴儿期和幼儿期因产钳助产导致围产期出生创伤的后遗症。我们报告一名13岁女孩,有2个月反复出现的、无痛性的耳前味觉性潮红病史,无出汗症状,最初怀疑是食物过敏。详细询问发现,在症状出现前7年有下颌髁突骨折的自行车事故史。我们的患者表现出儿童晚期耳颞部综合征的不寻常表现,即味觉性潮红类似食物过敏。认识到这种变异型对于及时识别至关重要,从而避免不必要的实验室检查,尤其是因为这种情况通常会自行缓解。

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Auriculotemporal Frey syndrome not associated with surgery or diabetes: systematic review.不与手术或糖尿病相关的耳颞神经综合征:系统评价。
Eur J Pediatr. 2022 May;181(5):2127-2134. doi: 10.1007/s00431-022-04415-w. Epub 2022 Feb 19.
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Frey's syndrome: A review of the physiology and possible role of neurotrophic factors.弗雷氏综合征:神经营养因子的生理学及可能作用综述
Laryngoscope Investig Otolaryngol. 2021 Apr 8;6(3):420-424. doi: 10.1002/lio2.559. eCollection 2021 Jun.
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Frey's syndrome as a differential diagnosis for food allergy: a case report.
弗雷氏综合征作为食物过敏的鉴别诊断:一例报告
BJGP Open. 2017 Feb 15;1(1):bjgpopen17X100653. doi: 10.3399/bjgpopen17X100653.
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Frey syndrome following herpes zoster in an otherwise healthy girl.一名原本健康的女孩患带状疱疹后出现了耳颞神经综合征。
BMJ Case Rep. 2018 Jul 25;2018:bcr-2018-224548. doi: 10.1136/bcr-2018-224548.
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Post Herpetic Frey's Syndrome.疱疹后弗雷综合征
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Case 2: Unilateral facial flushing with eating.病例2:进食时单侧面部潮红。
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