Dizon M V, Fischer G, Jopp-McKay A, Treadwell P W, Paller A S
Department of Pediatrics, Children's Memorial Hospital, Northwestern University Medical School, Chicago, III, USA.
Arch Dermatol. 1997 Sep;133(9):1143-5.
Patients with auriculotemporal nerve syndrome (Frey syndrome) have facial flushing, sweating, or both localized to the distribution of the auriculotemporal nerve that occurs in response to gustatory stimuli. In adults, the syndrome usually results from surgical injury or trauma to the parotid gland. The condition is rare in infants, but usually manifests during infancy with the introduction of solid food, thus leading to the misdiagnosis of food allergy by physicians unfamiliar with the syndrome.
We describe 8 children with auriculotemporal nerve syndrome who manifested with flushing only. The reaction was erroneously attributed to food allergy in most cases. Six of the 8 patients were delivered with forceps assistance. The remaining 2 patients, with disease onset during the first 3 months of life, had bilateral involvement without known trauma.
Auriculotemporal nerve syndrome may manifest during infancy as flushing with eating food. In contrast to the syndrome in adults, gustatory sweating is rarely associated. The known use of forceps to assist in the delivery of at least 14 of the 28 previously reported pediatric cases and in 6 of our 8 patients suggests that trauma to the parotid region may be responsible for the condition in most infants, as it is in adults. Auriculotemporal nerve syndrome in infancy should be recognized as a benign condition that often resolves spontaneously. Treatment is ineffective and unnecessary.
耳颞神经综合征（Frey综合征）患者在味觉刺激时，面部会出现潮红、出汗或两者皆有，且局限于耳颞神经分布区域。在成人中，该综合征通常由腮腺手术损伤或创伤引起。在婴儿中这种情况较为罕见，但通常在引入固体食物的婴儿期出现，从而导致不熟悉该综合征的医生误诊为食物过敏。
我们描述了8例仅表现为潮红的耳颞神经综合征患儿。在大多数情况下，这种反应被错误地归因于食物过敏。8例患者中有6例是通过产钳助产出生的。其余2例在出生后前3个月发病，双侧受累，无已知创伤史。
耳颞神经综合征在婴儿期可能表现为进食时潮红。与成人的综合征不同，很少伴有味觉性出汗。在之前报道的28例儿科病例中，已知至少14例以及我们的8例患者中有6例使用产钳助产，这表明腮腺区域的创伤可能是大多数婴儿发病的原因，与成人情况相同。婴儿期耳颞神经综合征应被视为一种通常会自发缓解的良性疾病。治疗无效且不必要。
