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[老年患者经皮内镜下胃造口术的并发症:局部皮肤感染和呼吸道感染]

[Complications of percutaneous endoscopic gastrostomy in the elderly: local skin infection and respiratory infection].

作者信息

Kanie J, Kono K, Kono T, Osawa M, Yamamoto T, Akatsu H, Shimokata H, Iguchi A

机构信息

Department of Internal Medicine, Kainan Hospital.

出版信息

Nihon Ronen Igakkai Zasshi. 2000 Feb;37(2):143-8. doi: 10.3143/geriatrics.37.143.

Abstract

We investigated post-operative management of acute complications of percutaneous endoscopic gastrostomy (PEG) which often caused respiratory infections and local skin infections. The subjects were a total of 341 patients (male 131, female 210, and the mean age was 80.3), they were classified into six groups by method of feeding and use of antibiotics. Patients were divided into three groups based on the time that feeding was started. In Group I, enteral feeding was not started within the first five days. In Group II, sterilized enteral feeding (lactated Ringer's solution for intravenous infusion) using sterilized intravenous infusion kit started within 24 hours after the procedure, and in Group III, feeding of the usual enteral formula started within 24 hours after the procedure. And as for the using of antibiotics, they were also divided into two groups, antibiotics administered[AB (+)] and no antibiotics administered[AB (-)]. Thus, the patients were divided into six groups according to the time of starting nutrition and the use of antibiotics. The rates of incidence of acute respiratory infections and local skin infections in the six groups were compared by the chi-square test and differences in the rates of incidence of complication were also compared between two PEG methods; the Pull/Push method and the Introducer method. The frequency of local skin infection in Group III was significantly higher than in Group I and Group II. As for the PEG methods, the frequency of local skin infection in the Pull/Push method was significantly higher than Introducer methods. Acute respiratory infections occurred significantly less in the AB (+) group than in the AB (-) group. Postoperative administration of antibiotics would seem to be appropriate for prophylaxis of respiratory infection in elderly patients after PEG. On the other hand, local skin infections are not related to administration of antibiotics, and are highly related to the method of feeding. We concluded that nutrition of sterilized enteral feeding immediately after operation using a sterilized intravenous infusion kit and administration of antibiotics are advisable to prevent major complications in elderly patients.

摘要

我们研究了经皮内镜下胃造口术(PEG)急性并发症的术后管理,这些并发症常导致呼吸道感染和局部皮肤感染。研究对象共有341例患者(男性131例,女性210例,平均年龄80.3岁),根据喂养方法和抗生素使用情况分为六组。患者根据开始喂养的时间分为三组。第一组在术后五天内未开始肠内喂养。第二组在术后24小时内使用无菌静脉输液套件开始无菌肠内喂养(静脉输注乳酸林格氏液),第三组在术后24小时内开始使用常规肠内配方进行喂养。至于抗生素的使用,也分为两组,即使用抗生素[AB(+)]和未使用抗生素[AB(-)]。因此,患者根据营养开始时间和抗生素使用情况分为六组。通过卡方检验比较六组中急性呼吸道感染和局部皮肤感染的发生率,并比较两种PEG方法(Pull/Push法和导入器法)并发症发生率的差异。第三组局部皮肤感染的发生率显著高于第一组和第二组。至于PEG方法,Pull/Push法局部皮肤感染的发生率显著高于导入器法。AB(+)组急性呼吸道感染的发生率明显低于AB(-)组。术后使用抗生素似乎适合预防老年患者PEG术后的呼吸道感染。另一方面,局部皮肤感染与抗生素使用无关,而与喂养方法高度相关。我们得出结论,术后立即使用无菌静脉输液套件进行无菌肠内喂养和使用抗生素对预防老年患者的主要并发症是可取的。

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