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体外经皮内镜下胃造口术(E-PEG)的成功新方法。

Successful new method of extracorporeal percutaneous endoscopic gastrostomy (E-PEG).

作者信息

Toyama Yoichi, Usuba Teruyuki, Son Kyonsu, Yoshida Seiya, Miyake Ryou, Ito Ryusuke, Tsuboi Kazuto, Kashiwagi Hideyuki, Tajiri Hisao, Yanaga Katsuhiko

机构信息

Department of Surgery, Jikei University School of Medicine, Kashiwa, Chiba, Japan.

出版信息

Surg Endosc. 2007 Nov;21(11):2034-8. doi: 10.1007/s00464-007-9270-4. Epub 2007 Apr 3.

Abstract

BACKGROUND

Although percutaneous endoscopic gastrostomy (PEG) has become popular for patients with swallowing disorders as a nutrition support or a decompressant of gastrointestine, perioperative complications associated with PEG have not decreased, especially peristomal infections. To reduce peristomal infections, we designed a new method of gastrostomy by extracorporeal approach under endoscopic observation, named as extra-corporeal PEG (E-PEG).

METHODS

Experimental studies for E-PEG were performed repeatedly using pigs under general anesthesia to confirm the safety of its procedure for human use. After approval of institutional ethics review board in our university, thirty patients with prior consent participated in this study. The operation time, the incidence rate of complications and the hospital stay were compared between E-PEG and ordinary pull-method PEG groups.

RESULTS

Two patients (6.7%) in E-PEG group had postoperative complications, i.e., aspiration pneumonia and surgical site infection. The operation time of E-PEG group was 5-16 (mean +/- SD: 10.3 +/- 2.96) min as compared to 14-37 (mean +/- SD: 26.9 +/- 8.39) min with pull-method PEG. The postoperative hospital day of E-PEG was within two days except for the two complicated cases. Significance differences of operation time, complication rate and postoperative hospital stay between those groups observed statistically.

CONCLUSIONS

These results indicate that E-PEG was safe, tolerable and speedy when compared ordinary pull-method PEG.

摘要

背景

尽管经皮内镜下胃造口术(PEG)已成为吞咽障碍患者营养支持或胃肠减压的常用方法,但与PEG相关的围手术期并发症并未减少,尤其是造口周围感染。为减少造口周围感染,我们设计了一种在内镜观察下经体外途径的新型胃造口术方法,称为体外PEG(E-PEG)。

方法

在全身麻醉下对猪反复进行E-PEG的实验研究,以确认其用于人体的安全性。在我校机构伦理审查委员会批准后,并经患者事先同意,30例患者参与了本研究。比较了E-PEG组和普通牵拉法PEG组的手术时间、并发症发生率和住院时间。

结果

E-PEG组有2例患者(6.7%)出现术后并发症,即吸入性肺炎和手术部位感染。E-PEG组的手术时间为5 - 16(平均±标准差:10.3±2.96)分钟,而牵拉法PEG组为14 - 37(平均±标准差:26.9±8.39)分钟。除2例并发症患者外,E-PEG组术后住院天数在2天以内。两组间手术时间、并发症发生率和术后住院时间的差异有统计学意义。

结论

这些结果表明,与普通牵拉法PEG相比,E-PEG安全、可耐受且速度快。

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