Hidayet N M, Sharaf S A, Aref S R, Tawfik T A, Moubarak I I
Faculty of Medicine, University of Alexandria, Egypt.
East Mediterr Health J. 1999 Mar;5(2):307-19.
Differences in the age at natural menopause were examined using a retrospective population sample of 289 naturally menopausal women. The mean age at natural menopause was 46.70 +/- 5.44 years. Earlier menopause occurred in women living in semiurban areas, divorced/separated and less educated women, and women who were younger at: first marriage, widowhood, divorce/separation and first or last full-term pregnancy. Later menopause occurred in women who had: irregular menstrual periods before 25 years, dysmenorrhoea and mid-cycle spotting. Duration of oral contraceptives use, weight and body mass index were significantly positively correlated with age at natural menopause. Multiple regression analyses indicated that age at last full-term pregnancy, residence, pattern of menstrual cessation and duration of oral contraceptive use were the significant predictors of the end of menstrual activity.
利用289名自然绝经女性的回顾性人群样本,研究了自然绝经年龄的差异。自然绝经的平均年龄为46.70±5.44岁。居住在半城市地区、离婚/分居且受教育程度较低的女性,以及初婚、丧偶、离婚/分居和首次或末次足月妊娠时年龄较小的女性绝经较早。月经周期不规律、痛经和月经中期点滴出血的女性绝经较晚。口服避孕药的使用时长、体重和体重指数与自然绝经年龄呈显著正相关。多元回归分析表明,末次足月妊娠年龄、居住地、月经停止模式和口服避孕药使用时长是月经活动结束的显著预测因素。