急性淋巴细胞白血病中的视网膜色素上皮变性、部分视网膜萎缩和黄斑裂孔。

Retinal pigment epithelial degeneration, partial retinal atrophy and macular hole in acute lymphocytic leukemia.

作者信息

Inkeles D M, Friedman A H

出版信息

Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975;194(4 Suppl):253-61. doi: 10.1007/BF00414672.

Abstract

A seven year old child with acute lymphocytic leukemia presented at autopsy with a macular hole, and degeneration of the retinal pigment epithelium and its overlying photoreceptors. She had been treated with cobalt 60, methotrexate, vincristine cyclophosphamide and prednisone. A review of the literature of similar findings as well as pigment epithelial degenerations from other causes is presented.

摘要

一名患有急性淋巴细胞白血病的7岁儿童尸检时发现有黄斑裂孔，视网膜色素上皮及其上方的光感受器发生变性。她曾接受过钴60、甲氨蝶呤、长春新碱、环磷酰胺和泼尼松治疗。本文综述了类似发现的文献以及其他原因导致的色素上皮变性。