新加坡翼状胬肉发病的危险因素：一项基于医院的病例对照研究。
Risk factors for the development of pterygium in Singapore: a hospital-based case-control study.
作者信息
Saw S M, Banerjee K, Tan D
机构信息
Department of Community, Occupational & Family Medicine, National University of Singapore.
出版信息
Acta Ophthalmol Scand. 2000 Apr;78(2):216-20. doi: 10.1034/j.1600-0420.2000.078002216.x.
PURPOSE
A hospital-based case-control study, designed to evaluate the risk factors for the development of pterygium in Singapore.
METHODS
Sixty-one cases and 125 controls were interviewed at the Singapore National Eye Centre. Information on present and past (5 and 10 years ago) exposure to sunlight on weekdays and weekends, sociodemographic data, behavior lifestyle and family history of eye disease was collected.
RESULTS
Patients with pterygia were mostly males, smoked and drank alcohol more often, had lower combined family incomes and were more likely to have a family history of eye disease. The adjusted odds ratios for the development of pterygia were 1.27 (95 percent confidence interval 1.06 to 1.54) and 1.31 (95 percent confidence interval 1.09 to 1.57) for participants who had spent more time in the sun five and ten years ago respectively.
CONCLUSIONS
Pterygium is an important public health problem in Singapore and its development is related to the amount of sunlight exposure.
目的
一项基于医院的病例对照研究，旨在评估新加坡翼状胬肉发生的危险因素。
方法
在新加坡国家眼科中心对61例病例和125例对照进行了访谈。收集了关于当前和过去（5年及10年前）工作日和周末阳光暴露情况、社会人口统计学数据、行为生活方式以及眼科疾病家族史的信息。
结果
翼状胬肉患者大多为男性，吸烟和饮酒更为频繁，家庭总收入较低，且更有可能有眼科疾病家族史。对于5年前和10年前在阳光下暴露时间更长的参与者，翼状胬肉发生的调整后比值比分别为1.27（95%置信区间1.06至1.54）和1.31（95%置信区间1.09至1.57）。
结论
翼状胬肉是新加坡一个重要的公共卫生问题，其发生与阳光暴露量有关。
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