Hatcher C R, Jones E L, King S B, Gray B T, Nalley T N
Ann Surg. 1975 May;181(5):754-9. doi: 10.1097/00000658-197505000-00034.
Since the advent of saphenous vein bypass grafting as successful means of myocardial revascularization, a variety of coronary artery disease syndrome have come under surgical attack. The proper role of surgery in many of these coronary syndromes remains ill-defined. However, clear indications for surgical revascularization exist in patients with unstable angina pectoris, i.e., progressive angina and onset of rest pain and noctural angina in spite of adequate medical therapy. An analysis has been made of 100 consecutive patients with unstable angina pectoris who underwent myocardial revascularization over the past 2 years at the Woodruff Medical Center of Emory University. Included in this group are the following subgroups: 1) Emergency cases with pre-infarction angina (including Printzmetal angina); 2) Cases of combined valvular heart disease and coronary artery disease; and 3) Advanced coronary artery disease with certain complications of previous myocardial infarction. A discussion of the relative merits of saphenous vein grafts and internal mammary artery anastomoses is presented and indicates that the technique selected should be determined by the quality of the distal native coronary circulation. Surgical mortality and morbidity figures, patency rates of saphenous vein grafts and internal mammary artery anastomoses visualized postoperatively, and the number of patients wiht dramatic relief of angina pectoris in this series support current enthusiasms for available surgical techniques for myocardial revascularization.
自从隐静脉搭桥术成为心肌血运重建的成功方法以来,多种冠状动脉疾病综合征都已成为外科手术的治疗对象。在许多这类冠状动脉综合征中,手术的恰当作用仍不明确。然而,对于不稳定型心绞痛患者,即尽管进行了充分的药物治疗仍有进行性心绞痛、静息痛发作及夜间心绞痛的患者,手术血运重建有明确的指征。对过去两年间在埃默里大学伍德拉夫医学中心接受心肌血运重建的100例连续不稳定型心绞痛患者进行了分析。该组包括以下亚组:1)梗死前心绞痛的急诊病例(包括变异型心绞痛);2)瓣膜性心脏病合并冠状动脉疾病的病例;3)伴有既往心肌梗死某些并发症的晚期冠状动脉疾病。文中讨论了隐静脉移植和乳内动脉吻合术的相对优点,并指出所选择的技术应由远端冠状动脉自身循环的质量来决定。该系列的手术死亡率和发病率数据、术后可见的隐静脉移植和乳内动脉吻合术的通畅率,以及心绞痛明显缓解的患者数量,都支持了目前对现有心肌血运重建手术技术的热情。