Barrington K J
Pediatrics, Royal Victoria Hospital, 687 av des Pins O, Montreal, P. Quebec, Canada, H3A 1A1.
Cochrane Database Syst Rev. 2000;1999(2):CD000505. doi: 10.1002/14651858.CD000505.
This section is under preparation and will be included in the next issue.
To determine whether the position of the tip of an umbilical arterial catheter influences the frequency of ischemic events, aortic thrombosis, intraventricular hemorrhage, mortality or necrotising enterocolitis in newborn infants.
Randomized and quasi randomized controlled trials of umbilical catheterization use were obtained from the following sources: 1. Effective Care of the Newborn Infant, edited by JC Sinclair and MB Bracken. 2. Medline Search using Melvyl Medline Plus and the keyword headings 'Umbilic#', 'Catheter#' and subject heading 'Infant, Newborn' 3. Search of personal data files
Randomized trials in newborn infants of any birthweight or gestation. Comparison of high catheter placement with the tip above the diaphragm to a lower position just above the aortic bifurcation. Clinically important end points such as ischemic events or aortic thrombosis.
Five randomized controlled trials and one alternate assignment study had sufficiently detailed data to allow interpretation.
High placed umbilical artery catheters are associated with a lower incidence of clinical vascular complications, without an increase in any adverse sequelae. Intraventricular hemorrhage rates, death and necrotising enterocolitis are not more frequent with high compared to low catheters.
REVIEWER'S CONCLUSIONS: There appears to be no evidence to support the use of low placed umbilical artery catheters. High catheters should be used exclusively.
本节正在编写中,将在下一期发表。
确定脐动脉导管尖端位置是否会影响新生儿缺血性事件、主动脉血栓形成、脑室内出血、死亡率或坏死性小肠结肠炎的发生频率。
脐导管使用的随机和半随机对照试验来自以下来源:1. JC Sinclair和MB Bracken编辑的《新生儿有效护理》。2. 使用Melvyl Medline Plus和关键词“脐#”“导管#”以及主题词“婴儿,新生儿”进行医学文献数据库检索。3. 检索个人数据文件。
任何出生体重或孕周的新生儿随机试验。比较导管尖端置于膈肌上方的高位与主动脉分叉上方稍低位置的低位。缺血性事件或主动脉血栓形成等具有临床重要意义的终点。
五项随机对照试验和一项交替分配研究有足够详细的数据可供解读。
高位放置的脐动脉导管与临床血管并发症发生率较低相关,且无任何不良后遗症增加。与低位导管相比,高位导管的脑室内出血率、死亡率和坏死性小肠结肠炎发生率并不更高。
似乎没有证据支持使用低位放置的脐动脉导管。应仅使用高位导管。