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新生儿脐动脉导管:导管设计(端孔与侧孔)的影响

Umbilical artery catheters in the newborn: effects of catheter design (end vs side hole).

作者信息

Barrington K J

机构信息

Pediatrics, Royal Victoria Hospital, 687 av des Pins O, Montreal, P. Quebec, Canada, H3A 1A1.

出版信息

Cochrane Database Syst Rev. 2000;1999(2):CD000508. doi: 10.1002/14651858.CD000508.

Abstract

BACKGROUND

This section is under preparation and will be included in the next issue.

OBJECTIVES

To determine whether the design of an umbilical arterial catheter influences the frequency of ischemic events, aortic thrombosis, intraventricular hemorrhage, mortality or necrotising enterocolitis in newborn infants.

SEARCH STRATEGY

Randomized and quasi randomized controlled trials of umbilical catheterization use were obtained from the following sources: 1. Effective Care of the Newborn Infant, edited by JC Sinclair and MB Bracken. 2. Medline Search using Melvyl Medline Plus and the keyword headings 'Umbilic#', 'Catheter#' and subject heading 'Infant, Newborn' 3. Search of personal data files

SELECTION CRITERIA

Randomized trials in newborn infants of any birthweight or gestation. Comparison of end hole catheters with side hole catheters. Clinically important end points such as ischemic events or aortic thrombosis.

DATA COLLECTION AND ANALYSIS

There appears to be only a single trial which has addressed this issue (Wesstrom 1979).

MAIN RESULTS

End hole catheters are associated with a much decreased risk of aortic thrombosis compared to side hole catheters. RR = 0.27 (95% CI 0.11, 0.67)

REVIEWER'S CONCLUSIONS: Side hole catheters should be avoided for umbilical arterial catheterisation in the newborn.

摘要

背景

本节正在编写中,将在下一期发表。

目的

确定脐动脉导管的设计是否会影响新生儿缺血性事件、主动脉血栓形成、脑室内出血、死亡率或坏死性小肠结肠炎的发生频率。

检索策略

脐动脉导管插入术的随机和半随机对照试验来自以下来源:1. JC辛克莱和MB布莱肯编辑的《新生儿有效护理》。2. 使用Melvyl Medline Plus和关键词“脐带#”“导管#”以及主题词“婴儿,新生儿”进行医学文献数据库检索。3. 检索个人数据文件。

选择标准

任何出生体重或孕周的新生儿随机试验。端孔导管与侧孔导管的比较。缺血性事件或主动脉血栓形成等具有临床意义的终点。

数据收集与分析

似乎只有一项试验涉及了这个问题(韦斯特伦,1979年)。

主要结果

与侧孔导管相比,端孔导管发生主动脉血栓形成的风险显著降低。相对危险度=0.27(95%可信区间0.11,0.67)

综述作者结论

新生儿脐动脉导管插入术应避免使用侧孔导管。

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