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成人完全性直肠脱垂的手术治疗

Surgery for complete rectal prolapse in adults.

作者信息

Bachoo P, Brazzelli M, Grant A

机构信息

Health Services Research Unit, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, Aberdeenshire, UK, AB25 2ZD.

出版信息

Cochrane Database Syst Rev. 2000(2):CD001758. doi: 10.1002/14651858.CD001758.

Abstract

BACKGROUND

Complete rectal prolapse is a debilitating condition, which affects both the very young and the elderly and can cause faecal incontinence. The range of surgical methods available to correct the underlying anal sphincter or pelvic floor defects in complete rectal prolapse poses the question about the choice of the best operation.

OBJECTIVES

To determine the effects of surgery on the treatment of rectal prolapse in adults. The following specific issues have been addressed: I. Whether surgical intervention is better than no treatment; II. Whether an abdominal approach to surgery is better then a perineal approach; III. Whether one method for performing rectopexy is better than another; IV. Whether laparoscopic access is better than open access for surgery; V. Whether resection should be included in the procedure.

SEARCH STRATEGY

We searched the Cochrane Incontinence Group trials register, the Cochrane Colorectal Cancer Group trials register, the Cochrane Controlled Trials Register (Issue 2, 1999), Medline (up to March 1999), Embase (1998 up to January 1999), Sigle (1980 up to December 1996), Biosis (1998 up to March 1999), SCI (1998 up to March 1999), ISTP (1982 up to March 1999) and the reference lists of relevant articles. We hand searched the British Journal of Surgery 1995-8, and the Diseases of the Colon and Rectum 1995-8. We also searched the proceedings of the Association of Coloproctology, meeting 1999. Date of the most recent searches: March 1999.

SELECTION CRITERIA

All randomised or quasi-randomised trials of surgery in the management of rectal prolapse.

DATA COLLECTION AND ANALYSIS

Two reviewers independently selected studies from the literature, extracted data and assessed the methodological quality of eligible trials. The three primary outcome measures were number of patients with recurrent rectal prolapse, or residual mucosal prolapse or faecal incontinence.

MAIN RESULTS

Eight trials were included with a total of 264 participants. No trial included a group receiving no treatment, or anal encirclement, or Delormes procedure, or laparoscopic suture rectopexy, or laparoscopic resection rectopexy. One trial (20 participants) compared both perineal and abdominal resection rectopexy with pelvic floor repair; four trials (175 participants) compared different types of open rectopexy techniques; one trial (21 participants) compared laparoscopic with open mesh rectopexy; and two trials included comparisons between open resection rectopexy and rectopexy alone. In all comparisons data were few. There were no detectable differences in recurrent prolapse between abdominal and perineal approaches, although there was a suggestion that residual faecal incontinence was less common after abdominal surgery. There were no detectable differences between the methods used for fixation during rectopexy. Division, rather than preservation, of the lateral ligaments was associated with less recurrent prolapse but more post-operative constipation, although these findings were found in small numbers. There were too few data with which to compare laparoscopic with open surgery. Bowel resection during rectopexy was associated with lower rates of constipation, but again numbers were small.

REVIEWER'S CONCLUSIONS: The small number of relevant trials identified, and their small sample sizes together with other methodological weaknesses severely limit the usefulness of this review for guiding practice. It was impossible to identify or refute clinically important differences between the alternative surgical operations. Larger rigorous trials are needed to improve the evidence with which to define optimum surgical treatment.

摘要

背景

完全性直肠脱垂是一种使人衰弱的病症,影响着儿童和老年人,可导致大便失禁。用于纠正完全性直肠脱垂中潜在的肛门括约肌或盆底缺陷的手术方法众多,这就引发了关于最佳手术选择的问题。

目的

确定手术治疗成人直肠脱垂的效果。探讨了以下具体问题:I. 手术干预是否优于不治疗;II. 腹部手术入路是否优于会阴手术入路;III. 一种直肠固定术方法是否优于另一种;IV. 腹腔镜手术入路是否优于开放手术入路;V. 手术过程中是否应包括切除。

检索策略

我们检索了Cochrane尿失禁组试验注册库、Cochrane结直肠癌组试验注册库、Cochrane对照试验注册库(1999年第2期)、Medline(截至1999年3月)、Embase(1998年至1999年1月)、Sigle(1980年至1996年12月)、Biosis(1998年至1999年3月)、SCI(1998年至1999年3月)、ISTP(1982年至1999年3月)以及相关文章的参考文献列表。我们手工检索了《英国外科杂志》1995 - 1998年以及《结肠和直肠疾病》1995 - 1998年的文献。我们还检索了1999年结直肠外科学会会议的论文集。最近一次检索日期:1999年3月。

选择标准

所有关于直肠脱垂手术治疗的随机或半随机试验。

数据收集与分析

两位评价者独立从文献中选择研究、提取数据并评估符合条件试验的方法学质量。三个主要结局指标为直肠脱垂复发、残留黏膜脱垂或大便失禁的患者数量。

主要结果

纳入了8项试验,共264名参与者。没有试验纳入未治疗组、肛门环扎术组、德洛姆氏手术组、腹腔镜缝合直肠固定术组或腹腔镜切除直肠固定术组。一项试验(20名参与者)比较了会阴和腹部切除直肠固定术与盆底修复术;四项试验(175名参与者)比较了不同类型的开放直肠固定术技术;一项试验(21名参与者)比较了腹腔镜与开放网状直肠固定术;两项试验包括了开放切除直肠固定术与单纯直肠固定术的比较。在所有比较中,数据都很少。腹部和会阴手术入路在直肠脱垂复发方面没有可检测到的差异,尽管有迹象表明腹部手术后残留大便失禁较少见。直肠固定术中使用的固定方法之间没有可检测到的差异。切断而非保留侧韧带与较少的直肠脱垂复发相关,但术后便秘较多,尽管这些发现的病例数较少。用于比较腹腔镜手术与开放手术的数据太少。直肠固定术中进行肠切除与较低的便秘发生率相关,但同样病例数较少。

评价者结论

所确定的相关试验数量少,样本量小以及其他方法学上的不足严重限制了本综述对指导实践的有用性。无法确定或反驳不同手术操作之间临床上的重要差异。需要进行更大规模、更严谨的试验以改善用于确定最佳手术治疗方法的证据。

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