用于不完全流产的抗生素。
Antibiotics for incomplete abortion.
作者信息
May W, Gülmezoglu A M, Ba-Thike K
机构信息
Health Services Development, Human Resources for Health, WHO SEARO, Ring Road, New Delhi, India, 110002.
出版信息
Cochrane Database Syst Rev. 2000(2):CD001779. doi: 10.1002/14651858.CD001779.
OBJECTIVES
The value of routine antibiotics before surgical evacuation of the uterus in women incomplete abortion is controversial. In some health centres antibiotic prophylaxis is advised in others antibiotics are only prescribed when there is signs of infection. The objective of this review is to evaluate the effectiveness of routine antibiotic prophylaxis to women with incomplete abortion.
SEARCH STRATEGY
We searched the Cochrane Controlled Trials Register, MEDLINE and Popline. Date of last search: January 1999.
SELECTION CRITERIA
Randomised trials comparing a policy of routine antibiotic prophylaxis with no routine prophylaxis were eligible for inclusion.
DATA COLLECTION AND ANALYSIS
Data extraction was conducted by two reviewers independently. Trial quality was assessed.
MAIN RESULTS
One study involving 140 women was included. A second well-conducted trial was excluded because of high losses to follow-up. No differences were detected in postabortal infection rates with routine prophylaxis or control. However, compliance with antibiotic treatment was also low.
REVIEWER'S CONCLUSIONS: There is not enough evidence to evaluate a policy of routine antibiotic prophylaxis to women with incomplete abortion.
目的
对于不全流产女性在手术清宫前使用常规抗生素的价值存在争议。在一些医疗中心建议进行抗生素预防，而在其他地方仅在有感染迹象时才开具抗生素。本综述的目的是评估常规抗生素预防对不全流产女性的有效性。
检索策略
我们检索了Cochrane对照试验注册库、MEDLINE和Popline。末次检索日期：1999年1月。
选择标准
比较常规抗生素预防策略与不进行常规预防的随机试验符合纳入标准。
数据收集与分析
由两名评价员独立进行数据提取。对试验质量进行评估。
主要结果
纳入了一项涉及140名女性的研究。另一项实施良好的试验因随访失访率高而被排除。常规预防组与对照组在流产后感染率方面未发现差异。然而，抗生素治疗的依从性也较低。
综述作者的结论
没有足够的证据来评估对不全流产女性进行常规抗生素预防的策略。
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