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骨骺骨折-分离的软骨路径:磁共振成像评估——一项在兔身上进行的与组织学相关的实验研究

Cartilaginous path of physeal fracture-separations: evaluation with MR imaging--an experimental study with histologic correlation in rabbits.

作者信息

Jaramillo D, Kammen B F, Shapiro F

机构信息

Department of Radiology, Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.

出版信息

Radiology. 2000 May;215(2):504-11. doi: 10.1148/radiology.215.2.r00ap50504.

DOI:10.1148/radiology.215.2.r00ap50504
PMID:10796932
Abstract

PURPOSE

To define the transverse levels of intracartilaginous fractures by using magnetic resonance (MR) imaging and histologic analysis in experimental physeal fracture-separations.

MATERIALS AND METHODS

Physeal fracture-separations were evaluated with MR imaging in 28 distal femurs and 28 proximal tibias of 22 immature rabbits. The intraphyseal transverse level of injury was graded as juxtaepiphyseal (germinal or proliferative zones) or juxtametaphyseal (hypertrophic zone or zone of provisional calcification). Histologic sections from 23 specimens were studied to assess correlations. We assessed nonenhanced and gadolinium-enhanced T1-weighted, intermediate-weighted, T2-weighted, and spoiled gradient-recalled-echo T1-weighted images.

RESULTS

In all MR studies, the injury was visible as a cleft of signal intensity lower than the signal intensity of the physeal cartilage. Juxtaepiphyseal extension, seen in 18 (64%) of 28 fractures, was more frequent in the undulating central part of the distal femoral physis than in the flatter proximal tibial physis (P =.008). In 20 of 23 specimens, MR imaging and histologic findings had excellent correlation for the detection of fracture level and morphology.

CONCLUSION

The course and level of injury within the cartilage in physeal fracture-separations can be defined with MR imaging. Extension into the juxtaepiphyseal physis, a potential risk factor for growth arrest, is detectable with MR imaging; MR imaging and histologic findings correlate well.

摘要

目的

通过磁共振成像(MR)和组织学分析确定实验性骺板骨折分离中软骨内骨折的横向水平。

材料与方法

对22只未成熟兔的28个股骨远端和28个胫骨近端进行骺板骨折分离的MR成像评估。将骺板内损伤的横向水平分为近骨骺(生发层或增殖层)或近干骺端(肥大层或临时钙化层)。研究了23个标本的组织学切片以评估相关性。我们评估了非增强和钆增强的T1加权、中等加权、T2加权和扰相梯度回波T1加权图像。

结果

在所有MR研究中,损伤均表现为信号强度低于骺板软骨信号强度的裂隙。28例骨折中有18例(64%)出现近骨骺延伸,在股骨远端骺板起伏的中央部分比胫骨近端较平坦的骺板更常见(P = 0.008)。在23个标本中的20个中,MR成像和组织学结果在骨折水平和形态学检测方面具有极好的相关性。

结论

MR成像可确定骺板骨折分离中软骨内损伤的过程和水平。延伸至近骨骺骺板是生长停滞的潜在危险因素,MR成像可检测到;MR成像和组织学结果相关性良好。

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