Giladi N, Simon E S, Korczyn A D, Groozman G B, Orlov Y, Shabtai H, Drory V E
Department of Neurology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv, Israel.
Muscle Nerve. 2000 May;23(5):731-4. doi: 10.1002/(sici)1097-4598(200005)23:5<731::aid-mus10>3.0.co;2-#.
Clinical distinction of multiple system atrophy (MSA) from Parkinson's disease (PD) is often difficult. Several recent reports indicate that objective classification may be accomplished using electromyographic (EMG) testing of the anal or urethral sphincters, but some authors have found that these tests are not reliable for this purpose. We studied 13 patients with PD and 10 with probable MSA, as diagnosed by consensus of four movement disorders specialists, according to accepted clinical criteria. Anal sphincter EMG was performed blind to the clinical diagnosis. We found no significant differences in the mean duration of motor unit potentials (MUPs), mean MUP amplitude, or prevalence of polyphasic potentials, satellite potentials, very long duration MUPs, or spontaneous activity between the two groups. Thus, anal sphincter EMG does not differentiate between PD and MSA.
多系统萎缩（MSA）与帕金森病（PD）的临床鉴别往往很困难。最近的几份报告表明，使用肛门或尿道括约肌的肌电图（EMG）测试可能实现客观分类，但一些作者发现这些测试在此目的上并不可靠。我们根据公认的临床标准，对13例帕金森病患者和10例可能患有多系统萎缩的患者进行了研究，这些诊断由四位运动障碍专家共同做出。肛门括约肌肌电图检查在对临床诊断不知情的情况下进行。我们发现两组之间运动单位电位（MUPs）的平均持续时间、平均MUP波幅、多相电位、卫星电位、极长持续时间MUPs或自发活动的发生率均无显著差异。因此，肛门括约肌肌电图无法区分帕金森病和多系统萎缩。
