Qiu Feng, Liu Jian-guo, Li Li-ping, Song Dong-dong, Yao Wei, Qi Xiao-kun
Department of Neurology, Navy General Hospital, Beijing 100048, China.
Zhonghua Yi Xue Za Zhi. 2013 Jul 2;93(25):1958-61.
To evaluate the diagnostic value of external anal sphincter electromyography (EAS-EMG) versus urethral sphincter electromyography (US-EMG) in patients with multiple system atrophy (MSA).
A total of 27 MSA patients were examined with EAS and US-EMG as treatment group while 28 non-MSA subjects as control group. Spontaneous activities during relaxation, mean duration & amplitude of motor unit potential (MUP), percentage of polyphasic and variations during strong contraction were recorded and analyzed statistically.
There was significant difference in light contraction between MSA and non-MSA cases on both EAS-EMG and US-EMG (EAS-EMG, P < 0.001; US-EMG, P = 0.002) . Meanwhile, strong contraction and percentage of polyphasic showed significant differences between MSA and non-MSA cases on EAS-EMG only (strong contraction, P = 0.016; percentage of polyphasic, P = 0.004) . EAS-EMG showed more significant changes in neurogenic injury than US-EMG.
US-EMG and EAS-EMG are valuable for the diagnosis of MSA. The differences of multiple parameters of EAS-EMG were more significant than those of US-EMG for MSA cases. US-EMG may serve as a supplement of EAS-EMG in case of restriction.
评估肛门外括约肌肌电图（EAS - EMG）与尿道括约肌肌电图（US - EMG）对多系统萎缩（MSA）患者的诊断价值。
共27例MSA患者接受EAS和US - EMG检查作为治疗组，28例非MSA受试者作为对照组。记录静息时的自发活动、运动单位电位（MUP）的平均时限和波幅、多相波百分比以及强收缩时的变化，并进行统计学分析。
在轻收缩时，MSA组与非MSA组在EAS - EMG和US - EMG上均存在显著差异（EAS - EMG，P < 0.001；US - EMG，P = 0.002）。同时，仅在EAS - EMG上，MSA组与非MSA组在强收缩和多相波百分比方面存在显著差异（强收缩，P = 0.016；多相波百分比，P = 0.004）。EAS - EMG在神经源性损伤方面的变化比US - EMG更显著。
US - EMG和EAS - EMG对MSA的诊断有价值。对于MSA病例，EAS - EMG多个参数的差异比US - EMG更显著。在受限情况下，US - EMG可作为EAS - EMG的补充。
