Balasubramanian S, Shivram R, Padmasani L N
Department of Paediatrics, Sri Ramachandra Medical College, Porur, Chennai.
Indian J Pediatr. 1999 Jan-Feb;66(1):148-50. doi: 10.1007/BF02752376.
A 29 day old male infant presented with a history of fever, cough, increasing respiratory distress and abdominal distension from the 10th day of life. Examination revealed failure to thrive, marked tachypnea, pallor, hepatosplenomegaly and harsh vesicular breath sounds. Chest skiagram showed extensive broncho-pneumonic changes. As the infant did not respond to antibiotics, he was investigated for tuberculosis. The gastric aspirate smear showed plenty of acid fast bacilli (AFB) and culture showed M. tuberculosis growth. Endometrial biopsy of the mother showed tuberculous granuloma and acid fast bacilli and culture of the aspirate from endometrium grew M. tuberculosis. The need for endometrial biopsy of mothers of infants with congenital tuberculosis is highlighted.
一名29日龄男婴自出生第10天起出现发热、咳嗽、呼吸窘迫加重及腹胀病史。检查发现发育不良、明显呼吸急促、面色苍白、肝脾肿大及粗糙的水泡音。胸部X线片显示广泛的支气管肺炎改变。由于该婴儿对抗生素无反应，对其进行了结核病检查。胃抽吸物涂片显示大量抗酸杆菌（AFB），培养显示有结核分枝杆菌生长。母亲的子宫内膜活检显示结核性肉芽肿和抗酸杆菌，子宫内膜抽吸物培养长出结核分枝杆菌。强调了对先天性结核病婴儿母亲进行子宫内膜活检的必要性。
