Prolactin-thyroxine antagonism and the metamorphosis of visual pigments in Rana catesbeiana tadpoles.

The relationship between prolactin-thyroxin antagonism and the metamorphosis of visual pigments in larval amphibians has been investigated using bullfrog (Rana catesbeiana) tadpoles. Althought prolactin-thyroxine antagonism is demonstrable by morphological criteria, ovineprolactin does not appear to anatagonize thyroxine-induced rhodopsin synthesis. The hypothesisis offered that prolactin-thyroxine antagonism is the result of differential gene activities which are opposite in their physiological effects.