Shibahara T, Noma H, Takeda E, Hashimoto S
Department of Oral and Maxillofacial Surgery, Tokyo Dental College, Chiba, Japan.
J Oral Maxillofac Surg. 2000 May;58(5):495-9. doi: 10.1016/s0278-2391(00)90009-0.
This study was undertaken to investigate the morphologic changes in the forearm flap in the oral environment.
Histologic evaluation of biopsy specimens from 20 forearm flaps was done 1 to 75 months after intraoral reconstruction after treatment of cancer. Hematoxylin and eosin and Azan were used to stain the deparaffinized sections.
The clinical features of the grafted flap seemed to depend on the time since the operation. The cornified layer of the epidermis of the flaps showed thinning histologically.
After 11 months of exposure to an intraoral environment, "mucosalization" of the forearm flap is evident.