局部钙离子信号引起的吸引或排斥
Attraction or repulsion by local Ca(2+) signals.
作者信息
Petersen O H, Cancela J M
机构信息
MRC Secretory Control Research Group, Department of Physiology, University of Liverpool, UK.
出版信息
Curr Biol. 2000 Apr 20;10(8):R311-4. doi: 10.1016/s0960-9822(00)00438-3.
Abstract
Recent studies have shown that cytosolic Ca(2+) signals, generated on one side of a nerve growth cone, can induce turning either towards or away from the side of the Ca(2+) signal, depending on the global Ca(2+) level. The results indicate that local Ca(2+) signals may provide important directional cues for axon guidance.
摘要
最近的研究表明，在神经生长锥一侧产生的胞质Ca(2+)信号，可根据整体Ca(2+)水平诱导神经生长锥转向或背离Ca(2+)信号一侧。这些结果表明，局部Ca(2+)信号可能为轴突导向提供重要的方向线索。
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