Alsaadi T, Binder J R, Lazar R M, Doorani T, Mohr J P
Department of Neurology, Medical College of Wisconsin, Milwaukee 53226, USA.
Neurology. 2000 May 9;54(9):1864-6. doi: 10.1212/wnl.54.9.1864.
Pure topographic disorientation (TD), defined as impaired recall of routes in familiar surroundings, has been attributed to lesions of the right parahippocampus. The authors present three patients encountered consecutively with TD and compare them to previously published cases. Lesions causing TD included a right splenial/cuneus infarct, a right > left medial temporo-occipital infarct, and a left splenial infarct. TD as an isolated symptom may occur from lesion in a variety of posterior medial locations, including the parahippocampus, splenium, and retrosplenial cortex.
单纯性地形定向障碍（TD），定义为在熟悉环境中对路线的回忆受损，一直被认为是右侧海马旁回病变所致。作者连续介绍了3例TD患者，并将他们与先前发表的病例进行比较。导致TD的病变包括右侧压部/楔叶梗死、右侧大于左侧的颞枕内侧梗死以及左侧压部梗死。TD作为一种孤立症状可能源于多种后内侧部位的病变，包括海马旁回、压部和压后皮质。
