Berg R, Kendall R W, Duvoisin G E, Ganji J H, Rudy L W, Everhart F J
J Thorac Cardiovasc Surg. 1975 Sep;70(3):432-9.
Preservation of viable myocardium is the primary goal of coronary artery surgery. Our total experience with coronary artery bypass grafting is 1,612 patients, operated upon from March 13, 1969, through Jan. 31, 1975 (2.85 per cent over-all mortality rate). Four hundred thirteen patients were operated upon on an emergency basis. Of this group, 96 were having acute myocardial infarctions and 317 were in the preinfarction syndrome. Emergency coronary artery bypass surgery was performed with 5 deaths (5.2 per cent) in the acute myocardial infarction group and 4 deaths in the preinfarction group (1.26 per cent). These patients had a much lower mortality rate than that of medically treated patients in the acute myocardial infarction group. Postoperative catheterization studies on the acute myocardial infarction group showed a 96 per cent rate of primary graft patency. Follow-up studies through 3 years, 10 months show only 1 late death (4 months after the operation). The in-hospital and the first year mortality rates in a medically treated group with acute myocardial infarction were compared with the surgically treated group. The result was a mortality rate of 30 per cent with medical treatment and 6.3 per cent with surgical treatment. Actuarial analysis demonstrated a greater than 20 per cent difference in mortality rate at 1 year, in favor of surgical treatment. The lower surgical mortality coupled with the early and late clinical results prove that emergency coronary bypass is superior therapy in selected patients with acute myocardial infarction.
保存存活心肌是冠状动脉手术的主要目标。我们进行冠状动脉搭桥手术的总经验涉及1612例患者,手术时间从1969年3月13日至1975年1月31日(总体死亡率为2.85%)。413例患者接受了急诊手术。在这组患者中,96例发生急性心肌梗死,317例处于梗死前综合征。急诊冠状动脉搭桥手术在急性心肌梗死组有5例死亡(5.2%),梗死前组有4例死亡(1.26%)。这些患者的死亡率远低于急性心肌梗死组接受药物治疗的患者。对急性心肌梗死组术后进行的导管检查显示,移植血管一期通畅率为96%。随访3年10个月,仅1例晚期死亡(术后4个月)。对急性心肌梗死药物治疗组和手术治疗组的住院死亡率和第一年死亡率进行了比较。结果是药物治疗组死亡率为30%,手术治疗组为6.3%。精算分析表明,1年时死亡率差异大于20%,手术治疗更具优势。较低的手术死亡率以及早期和晚期临床结果证明,急诊冠状动脉搭桥术对选定的急性心肌梗死患者来说是更优的治疗方法。