蛋白质-蛋白质相互作用决定了信号转导中的特异性。 - Suppr

Protein-protein interactions define specificity in signal transduction.

作者信息

Pawson T, Nash P

机构信息

Program in Molecular Biology and Cancer, Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.

出版信息

Genes Dev. 2000 May 1;14(9):1027-47.

PMID:10809663

Abstract

摘要

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Protein-protein interactions define specificity in signal transduction.

作者信息

Pawson T, Nash P

机构信息

Program in Molecular Biology and Cancer, Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.

出版信息

Genes Dev. 2000 May 1;14(9):1027-47.

PMID:10809663

Abstract

摘要

相似文献

Protein-protein interactions define specificity in signal transduction.

Genes Dev. 2000 May 1;14(9):1027-47.

[Protein G as a "universal link" in signal transmission from the membrane receptors on their effectors--minireview].

Postepy Biochem. 1988;34(3):123-30.

Notch signaling: from the outside in.

Dev Biol. 2000 Dec 15;228(2):151-65. doi: 10.1006/dbio.2000.9960.

[Dynamic regulation of receptor transmembrane domain assembly during signal transmission across the plasma membrane].

Tanpakushitsu Kakusan Koso. 2005 Aug;50(10 Suppl):1226-32.

Signal transduction and endocytosis: close encounters of many kinds.

Nat Rev Mol Cell Biol. 2002 Aug;3(8):600-14. doi: 10.1038/nrm883.

Formation and maintenance of distinctive cell patterns by coexpression of membrane-bound ligands and their receptors.

Dev Dyn. 2002 Mar;223(2):180-92. doi: 10.1002/dvdy.10042.

The membrane protein universe: what's out there and why bother?

J Intern Med. 2007 Jun;261(6):543-57. doi: 10.1111/j.1365-2796.2007.01792.x.

Phospholipid scramblase 1 is imported into the nucleus by a receptor-mediated pathway and interacts with DNA.

Biochemistry. 2004 Mar 30;43(12):3518-26. doi: 10.1021/bi0356911.

Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling.

Nat Rev Mol Cell Biol. 2002 Sep;3(9):673-84. doi: 10.1038/nrm910.

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Zygote. 2000;8 Suppl 1:S28-30.

引用本文的文献

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J Chem Theory Comput. 2025 Sep 9;21(17):8557-8570. doi: 10.1021/acs.jctc.5c00736. Epub 2025 Aug 20.

Quantifying collective interactions in biomolecular phase separation.

Nat Commun. 2025 Aug 19;16(1):7724. doi: 10.1038/s41467-025-62437-y.

Bioluminescence-based assays for quantifying endogenous protein interactions in live cells.

J Biol Chem. 2025 Jul 4;301(8):110454. doi: 10.1016/j.jbc.2025.110454.

Unravelling the human taste receptor interactome: machine learning and molecular modelling insights into protein-protein interactions.

NPJ Sci Food. 2025 Jul 1;9(1):113. doi: 10.1038/s41538-025-00478-9.

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Biochemistry. 2025 Jul 1;64(13):2699-2711. doi: 10.1021/acs.biochem.5c00212. Epub 2025 Jun 15.

A Polyproline Type II Peptidomimetic Disrupts a Grb2 SH3C Domain Protein-Protein Interaction Implicated in Breast Cancer.

Chembiochem. 2025 Jul 18;26(14):e202500343. doi: 10.1002/cbic.202500343. Epub 2025 Jun 6.

The ascent of AKAPs, from architectural elements to kinase anchors: a perspective.

Biochem J. 2025 May 13;482(10):BCJ20253085. doi: 10.1042/BCJ20253085.

Protein Engineering for Spatiotemporally Resolved Cellular Monitoring.

Annu Rev Anal Chem (Palo Alto Calif). 2025 May;18(1):217-240. doi: 10.1146/annurev-anchem-070124-035857. Epub 2025 Feb 25.

The protein interactome of Escherichia coli carbohydrate metabolism.

PLoS One. 2025 Feb 4;20(2):e0315240. doi: 10.1371/journal.pone.0315240. eCollection 2025.

Quantitative Proteomics Analysis Reveals XDH Related with Ovarian Oxidative Stress Involved in Broodiness of Geese.

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Protein-protein interactions define specificity in signal transduction.

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Protein-protein interactions define specificity in signal transduction.

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