Joshi P S, Badwe R A
Tata Memorial Hospital, Parel, Mumbai, India.
Indian J Cancer. 1999 Mar;36(1):43-5.
Preoperative diagnosis of histology and receptor status is important in management of breast cancer. Percutaneous automated core biopsy with biopsy gun (Gun biopsy) was done in fifty patients with palpable breast lump in whom fine needle aspiration cytology (FNAC) was either negative or not done In all patients adequate tissue for histology and receptor status studies was obtained forty-two patients had infiltrating duct carcinoma and eight patients had benign lesions on gun biopsy. There were no complications in this procedure. Twenty of the forty-two patients underwent mastectomy either per primum or after chemotherapy, had the diagnosis substantiated on histopathological examination Thirty-four samples were examined for receptor status and the specimen was found to be adequate and of good quality. We conclude that gun biopsy is a simple and safe procedure which is more sensitive and specific than FNAC.
术前对组织学和受体状态进行诊断对乳腺癌的治疗很重要。对50例可触及乳腺肿块且细针穿刺细胞学检查(FNAC)结果为阴性或未进行该检查的患者进行了活检枪经皮自动芯针活检(枪式活检)。在所有患者中均获取了足够用于组织学和受体状态研究的组织。42例患者经枪式活检诊断为浸润性导管癌,8例为良性病变。该操作无并发症发生。42例患者中有20例最初或化疗后接受了乳房切除术,组织病理学检查证实了诊断。对34份样本进行了受体状态检测,发现标本足够且质量良好。我们得出结论,枪式活检是一种简单、安全的操作,比FNAC更敏感、更具特异性。