Pellegrini A, Gordini V, Gallotti R, Campolo L
G Ital Cardiol. 1975;5(2):184-92.
200 patients underwent bypass graft for treatment of severe coronary vessel disease. The bypass vein grafts were 316; single grafts in 100 cases, double in 85, triple in 14 and in 1 case a patient received 4 grafts. In 57 cases a previous coronary endarterectomy was performed. The flow in the graft at the end of the operation was more than 40 cc/min. in 80% of cases. 22 patients died. Postoperative myocardial infarction occurred in 14% of the patients. The mortality was higher in the preinfarction angina group, and less in the chronic angina group without concomitant surgery (7,2%) and is statistically in direct relation to the functional condition of the left ventricle (2,8% in patients with end diastolic left ventricular pressure less than 20 mmHg and without akinetic areas). Relief of angina was observed in 87% of the surviving patients. Postoperative coronarography, catheterism and left ventriculography was performed in 46 patients. Only 2 of the 15 cases with postoperative angina had the graft patent. Significant improvement of the left ventricular function with disappearence or regression of akinetic areas was observed in 9 patients. Our experience indicates that the value of this operation cannot be entirely known at the present time.
200例患者接受了搭桥手术以治疗严重的冠状动脉疾病。搭桥静脉血管共316条;100例为单条血管搭桥,85例为双条,14例为三条,1例患者接受了4条血管搭桥。57例患者曾接受过冠状动脉内膜切除术。手术结束时80%的病例血管血流量超过40毫升/分钟。22例患者死亡。14%的患者发生了术后心肌梗死。梗死前心绞痛组的死亡率较高,而无伴随手术的慢性心绞痛组死亡率较低(7.2%),且死亡率与左心室功能状况有统计学上的直接关系(左心室舒张末期压力小于20毫米汞柱且无运动不能区域的患者死亡率为2.8%)。87%的存活患者心绞痛症状得到缓解。46例患者进行了术后冠状动脉造影、心导管检查和左心室造影。术后心绞痛的15例患者中只有2例血管通畅。9例患者左心室功能显著改善,运动不能区域消失或缩小。我们的经验表明,目前尚不能完全了解该手术的价值。