Belleannée G, Verdebout J, Feoli F, Trouette H, de Mascarel A, Verhest A
Service d'Anatomie et Cytotologie Pathologiques, Hôpital Haut-Lévêque, CHU Bordeaux, Pessac, France.
Clin Exp Pathol. 1999;47(6):273-7.
Two experiences of peroperative diagnosis in thyroid surgery are reported. In Bordeaux (France), frozen sections are supplemented by touch smears. Imprints alone give results similar to frozen but are not suitable in differentiating follicular adenoma from carcinoma; they appear more accurate for recognising the follicular presentation of papillary carcinoma. Touch smear is a rapid cost-effective alternative to frozen section. In Brussels (Belgium), a more conventional attitude results in 185 frozen. A false negative ends in a follicular carcinoma. Eleven follicular proliferations will be signed out adenoma (8 cases) or carcinoma (3 cases) and three papillary carcinomas will only be detected after embedding. Six false negative derive from frozen section, no false positive is noted. An immediate change in the surgical procedure is justified twice. These observations argue for the free choice by the pathologist of the best technical procedure in peroperative diagnosis.
本文报道了甲状腺手术中两种术中诊断的经验。在法国波尔多，冰冻切片辅以触摸涂片。单独的印片结果与冰冻切片相似，但不适用于鉴别滤泡性腺瘤和癌；在识别乳头状癌的滤泡样表现方面似乎更准确。触摸涂片是一种快速且经济有效的替代冰冻切片的方法。在比利时布鲁塞尔，采用了更为传统的方法，进行了185次冰冻切片。一次假阴性结果导致了滤泡癌的出现。11例滤泡性增生将被诊断为腺瘤（8例）或癌（3例），3例乳头状癌仅在包埋后才被检测到。6例假阴性来自冰冻切片，未发现假阳性。有两次手术操作立即改变是合理的。这些观察结果支持病理学家在术中诊断时可自由选择最佳技术方法。
